mt-Nd2 - NADH dehydrogenase 2, mitochondrial Gene

Also Known as ND2

Species: Rattus norvegicus (strain: BN/SsNHsdMCW)

Gene Type: protein coding
Gene ID: 26194

Summary

Enables ionotropic glutamate receptor binding activity and protein kinase binding activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone and mitochondrial respiratory chain complex I assembly. Predicted to act upstream of or within Reactive Oxygen Species metabolic process. Located in mitochondrion and postsynaptic density. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder Cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2). [provided by Alliance of Genome Resources, Apr 2022]

mt-Nd2 Products (2)

mRNA Protein Name
YP_665630.1 NADH dehydrogenase subunit 2 (mitochondrion) [Rattus norvegicus]
YP_665630.1 NADH dehydrogenase subunit 2 (mitochondrion) [Rattus norvegicus]

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables ionotropic glutamate receptor binding IPI
IPI: Inferred from physical interaction
15069201 RGD
enables protein kinase binding IPI
IPI: Inferred from physical interaction
15069201 RGD
Biological Process GO Annotation Evidence References Source
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
33310031 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

  • NADH dehydrogenase subunit 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08797 MT-ND2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20570 mt-Nd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27078 mt-Nd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens mt-Nd2 NCBI NCBI:4536