Sars1 - seryl-tRNA synthetase 1 Gene

Also Known as Sars

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 266975

Summary

Predicted to enable several functions, including nucleic acid binding activity; protein homodimerization activity; and serine-tRNA Ligase activity. Predicted to be involved in negative regulation of angiogenesis; negative regulation of macromolecule metabolic process; and seryl-tRNA aminoacylation. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human SARS1 (seryl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]

Sars1 Products (1)

mRNA Protein Name
NM_001007606.1 NP_001007607.1 serine--tRNA ligase, cytoplasmic
Protein Preferred Names Protein Names

serine--tRNA ligase, cytoplasmic

  • serRS

  • seryl-aminoacyl-tRNA synthetase 1

  • seryl-tRNA synthetase, cytoplasmic

  • seryl-tRNA(Ser/Sec) synthetase

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P0205B Saralasin TFA Antagonist 99.37% Unkown
HY-P0205 Saralasin Antagonist 99.46% Unkown
HY-P1564A [Sar1, Ile8]-Angiotensin II TFA 99.85% Unkown
HY-P0205A Saralasin acetate hydrate Antagonist / Unkown
HY-P1564 [Sar1, Ile8]-Angiotensin II / Unkown

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P4685 (Sar1,Ile4,8)-Angiotensin II Agonist 98.23% Unkown
HY-P3138 (Sar1)-Angiotensin II Agonist 99.84% Unkown
HY-RS12442 SAR1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-172265 FKBP12 PROTAC FM4 Degrader 99.95% Unkown
HY-P10640 [Sar1,Thr8]-Angiotensin II Antagonist / Unkown
HY-P11389 (Sar1,Gly8)-Angiotensin II Antagonist / Unkown
HY-RS12443 SAR1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12448 SARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-101823A A-81282 Antagonist / Unkown
HY-RS20487 Sar1a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26995 Sar1a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W140555 5,7-Dimethoxyphthalide Inhibitor 99.97% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sars1 NCBI NCBI:6301