Etv3 - ets variant 3 Gene

Also Known as Pe1; METS

Species: Mus musculus

Gene Type: protein coding
Gene ID: 27049

Summary

Enables DEAD/H-box RNA helicase binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in cellular response to granulocyte macrophage colony-stimulating factor stimulus and negative regulation of cell population proliferation. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in chromatin. Part of RNA polymerase II transcription repressor complex. Is expressed in several structures, including central nervous system; dorsal root ganglion; early conceptus; genitourinary system; and retina. Orthologous to human ETV3 (ETS variant transcription factor 3). [provided by Alliance of Genome Resources, Apr 2022]

Etv3 Products (7)

mRNA Protein Name
NM_001083318.3 NP_001076787.1 ETS translocation variant 3 isoform 1
NM_001286844.2 NP_001273773.1 ETS translocation variant 3 isoform 1
NM_001359750.2 NP_001346679.1 ETS translocation variant 3 isoform 2
NM_001411078.1 NP_001398007.1 ETS translocation variant 3 isoform 2
NM_001411079.1 NP_001398008.1 ETS translocation variant 3 isoform 3
NM_001411080.1 NP_001398009.1 ETS translocation variant 3 isoform 3
NM_012051.5 NP_036181.3 ETS translocation variant 3 isoform 1
Protein Preferred Names Protein Names

ETS translocation variant 3

  • ETS domain transcriptional repressor PE1

  • ETS-domain protein

  • ets variant gene 3

  • mitogenic Ets transcriptional suppressor METS

Orthologs Information

Species Symbol Source ID
Homo sapiens Etv3 NCBI NCBI:2117