GML - glycosylphosphatidylinositol anchored molecule like Gene

Also Known as LY6DL

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2765

About GML

Cytogenetic location: 8q24.3 Genomic coordinates (GRCh38): 8:142,834,801-142,846,851 (from NCBI)

This gene has 2 transcripts (splice variants), 55 orthologues and 1 paralogue. Low expression observed in reference dataset.

Summary

Predicted to be involved in DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; apoptotic process; and negative regulation of cell population proliferation. Predicted to be extrinsic component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

GML Products (1)

mRNA Protein Name
NM_002066.3 NP_002057.1 glycosyl-phosphatidylinositol-anchored molecule-like protein precursor
Protein Preferred Names Protein Names

glycosyl-phosphatidylinositol-anchored molecule-like protein

  • GPI anchored molecule like protein

Related Diseases

Diseases Alias
Large Congenital Melanocytic Nevus

  • Giant Pigmented Hairy Nevus

  • Giant Congenital Melanocytic Nevus

  • Gmn

  • Congenital Pigmented Nevus

  • Lcmn

  • Gphn

  • Giant Congenital Nevus

  • Bathing Trunk Nevus

  • Congenital Giant Pigmented Nevus

  • Congenital Hairy Nevus

  • Giant Hairy Nevus

  • Giant Pigmented Nevus

  • Congenital Giant Pigmented Nevus Of Skin

  • Congenital Melanocytic Nevus Syndrome

  • Giant Congenital Melanocytic Nevi

  • Giant Congenital Pigmented Nevus

  • Melanocytic Nevus Syndrome, Congenital
Peroneal Nerve Paralysis

  • Peroneal Nerve Palsy
Cantu Syndrome

  • Hypertrichotic Osteochondrodysplasia

  • Hypertrichotic Osteochondrodysplasia Cantu Type

  • Cantú Syndrome

  • Craniofaciocardioskeletal Syndrome

  • Hypertrichosis-Osteochondrodysplasia-Cardiomegaly Syndrome

  • Congenital Hypertrichosis-Acromegaloid Facial Features Spectrum

  • Congenital Hypertrichosis-Coarse Facial Features Spectrum

  • HTOCD

  • Osteochondrodysplasia, Hypertrichotic
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Approval
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P1956 HSA Protein Inhibitor 99.9% Unkown
HY-B1831A Oritavancin diphosphate Inhibitor 99.71% Unkown
HY-B1831 Oritavancin Inhibitor / Unkown

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19805 STO-609 Inhibitor 98.20% Unkown
HY-P1956A HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) Inhibitor 99.60% Unkown
HY-W111690 Manganese(II) chloride bislithium chloride complex solution,0.956 g/mL at 25 °C, 0.5M in THF / Unkown
HY-19805A STO-609 acetate Inhibitor / Unkown
HY-168371 1-Palmitoyl-2-13(S)-HODE-sn-glycero-3-PC / Unkown
HY-N21984 (3S,4S)-4-Hydroxy-3,6-dimethyl-3,4-dihydronaphthalen-1(2H)-one / Unkown
HY-N8256 (–)-Mycousnine Inhibitor / Unkown
HY-N9179 3′,4′,5′,5,6,7-Hexamethoxyflavone Inhibitor 99.06% Unkown
HY-RS05521 GML Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N13938 Azinomycin A / Unkown
HY-N14558 3',8-Dihydroxy-4',6,7-trimethoxyisoflavone / Unkown
HY-N15046 Barminomycin I / Unkown
HY-N15047 Barminomycin II / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GML RGD RGD:1307850
Macaca mulatta GML VGNC VGNC:73081
Bos taurus GML VGNC VGNC:29437
Others GML NCBI