PURG - purine rich element binding protein G Gene
Also Known as PURGA; PURGB; PURG-A; PURG-B
Species: Homo sapiens
About PURG
This gene has 3 transcripts (splice variants), 196 orthologues and 2 paralogues. Biased expression in brain (RPKM 1.4), testis (RPKM 1.1) and 12 other tissues.
Summary
The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016]
PURG Products (4)
| mRNA | Protein | Name |
|---|---|---|
| NM_001015508.3 | NP_001015508.1 | purine-rich element-binding protein gamma isoform B |
| NM_001323311.2 | NP_001310240.1 | purine-rich element-binding protein gamma isoform A |
| NM_001323312.2 | NP_001310241.1 | purine-rich element-binding protein gamma isoform B |
| NM_013357.2 | NP_037489.1 | purine-rich element-binding protein gamma isoform A |
PURG Protein Structure
PurA: PurA ssDNA and RNA-binding protein (57 - 321)
- 0
- 100
- 200
- 300
- 347 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
purine-rich element-binding protein gamma |
|
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Macaca mulatta | PURG | VGNC | VGNC:76506 |
| Mus musculus | PURG | MGD | MGI:1922279 |
| Canis familiaris | PURG | VGNC | VGNC:45209 |
| Felis catus | PURG | VGNC | VGNC:64438 |
| Rattus norvegicus | PURG | RGD | RGD:1305088 |
| Bos taurus | PURG | VGNC | VGNC:59359 |
| Others | PURG | NCBI |