2. Gene
  3. PURG - purine rich element binding protein G Gene

PURG - purine rich element binding protein G Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as PURGA; PURGB; PURG-A; PURG-B

Gene ID: 29942 | Gene type: protein coding

About PURG

Cytogenetic location: 8p12 Genomic coordinates (GRCh38): 8:30,995,802-31,033,356 (from NCBI)

This gene has 3 transcripts (splice variants), 196 orthologues and 2 paralogues. Biased expression in brain (RPKM 1.4), testis (RPKM 1.1) and 12 other tissues.

Summary

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016]

PURG Products(4)

mRNA Protein Name
NM_001015508.3 NP_001015508.1 purine-rich element-binding protein gamma isoform B
NM_001323311.2 NP_001310240.1 purine-rich element-binding protein gamma isoform A
NM_001323312.2 NP_001310241.1 purine-rich element-binding protein gamma isoform B
NM_013357.2 NP_037489.1 purine-rich element-binding protein gamma isoform A

PURG Protein Structure

PurA

PurA: PurA ssDNA and RNA-binding protein (57 - 321)

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  • 347 a.a.
Protein Preferred Names Protein Names

purine-rich element-binding protein gamma

Pur-gamma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS11466 PURG Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta PURG VGNC VGNC:76506
Mus musculus PURG MGD MGI:1922279
Canis familiaris PURG VGNC VGNC:45209
Felis catus PURG VGNC VGNC:64438
Rattus norvegicus PURG RGD RGD:1305088
Bos taurus PURG VGNC VGNC:59359