Efemp1 - EGF containing fibulin extracellular matrix protein 1 Gene

Also Known as T16

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 305604

Summary

Predicted to enable epidermal growth factor receptor binding activity and epidermal growth factor-activated receptor activity. Involved in positive regulation of cell population proliferation; regulation of cell projection organization; and regulation of glial cell migration. Located in basement membrane and cytoplasm. Human ortholog(s) of this gene implicated in Doyne honeycomb retinal dystrophy. Orthologous to human EFEMP1 (EGF containing fibulin extracellular Matrix Protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Efemp1 Products (1)

mRNA Protein Name
NM_001012039.1 NP_001012039.1 EGF-containing fibulin-like extracellular matrix protein 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9268694 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of neuron projection development IDA
IDA: Inferred from direct assay
18803302 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
18803302 RGD
involved in positive regulation of cell projection organization IDA
IDA: Inferred from direct assay
18803302 RGD
involved in positive regulation of cell projection organization IMP
IMP: Inferred from mutant phenotype
18803302 RGD
involved in regulation of glial cell migration IDA
IDA: Inferred from direct assay
18803302 RGD
Cellular Component GO Annotation Evidence References Source
located in basement membrane IDA
IDA: Inferred from direct assay
18803302 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EGF-containing fibulin-like extracellular matrix protein 1

  • FIBL-3

  • epidermal growth factor-containing fibulin-like extracellular matrix protein 1

  • fibulin-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04185 EFEMP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18005 Efemp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24477 Efemp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Efemp1 NCBI NCBI:2202