INSR - insulin receptor Gene

Also Known as ir-A

Species: Bos taurus

Gene Type: protein coding
Gene ID: 408017

About INSR

Primary_assembly 7: 16,058,828-16,183,062 reverse strand.ARS-UCD1.2:CM008174.2

This gene has 10 transcripts (splice variants), 289 orthologues and 56 paralogues.

INSR Products (4)

mRNA Protein Name
XM_002688832.6 XP_002688878.3 insulin receptor isoform X1
XM_005208816.4 XP_005208873.1 insulin receptor isoform X3
XM_005208815.4 XP_005208872.1 insulin receptor isoform X2
XM_005208817.4 XP_005208874.1 insulin receptor isoform X4

INSR Protein Structure

Recep_L_domain

Recep_L_domain: pfam01030 (51 - 163)

Furin-like

Furin-like: pfam00757 (178 - 336)

Recep_L_domain

Recep_L_domain: pfam01030 (358 - 471)

FN3

FN3: cd00063 (621 - 664)

FN3

FN3: cd00063 (866 - 943)

Insulin_TMD

Insulin_TMD: pfam17870 (939 - 986)

PTKc_InsR

PTKc_InsR: cd05061 (1015 - 1302)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1382 a.a.
Protein Preferred Names Protein Names

insulin receptor

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-15656 Ceritinib Inhibitor 99.95% Yes
HY-15656A Ceritinib dihydrochloride Inhibitor 99.90% Yes
HY-15656AR Ceritinib dihydrochloride (Standard) Inhibitor / Unkown
HY-15656R Ceritinib (Standard) Inhibitor 99.72% Unkown

Clinical Phase

Inhibitory Antibodies (2)
Cat. No. Product Name Effect
Purity Phase
HY-P990712 Ersodetug Inhibitor 99.33% Phase 3
HY-P991037 Verenafusp alfa / Phase 1

Pre-clinical Phase

Bioactive Molecules (15)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-50866 NVP-AEW541 99.92% Unkown
HY-13203 NVP-TAE 226 99.77% Unkown
HY-10252 NVP-ADW742 99.30% Unkown
HY-15656S Ceritinib-d7 Inhibitor 98.00% Unkown
HY-RS06847 Insr Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-50866B NVP-AEW541 dihydrochloride / Unkown
HY-10252A cis-NVP-ADW742 Inhibitor / Unkown
HY-108230 ALK-IN-12 Inhibitor / Unkown
HY-15656B Ceritinib mesylate Inhibitor / Unkown
HY-169066 INSR agonist 1 Agonist / Unkown
HY-180972 PROTAC EML4-ALK Degrader-2 Inhibitor / Unkown
HY-183292 SH-1092 Inhibitor / Unkown
HY-E70730 INSR Recombinant Human Active Protein Kinase / Unkown
HY-RS06846 INSR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06848 Insr Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991290 IRAB-B Antagonist 98.30% Unkown
HY-P991291 XOMA 129 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens INSR NCBI NCBI:3643