MUC6 - mucin 6, oligomeric mucus/gel-forming Gene

Also Known as MUC-6

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 4588

About MUC6

Cytogenetic location: 11p15.5 Genomic coordinates (GRCh38): 11:1,012,823-1,036,718 (from NCBI)

This gene has 4 transcripts (splice variants), 1 gene allele, 94 orthologues and 19 paralogues. Biased expression in stomach (RPKM 174.6) and duodenum (RPKM 41.3).

Summary

This gene encodes a member of the Mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. [provided by RefSeq, Dec 2016]

MUC6 Products (1)

mRNA Protein Name
NM_005961.3 NP_005952.2 mucin-6 precursor

MUC6 Protein Structure

VWD

VWD: von Willebrand factor type D domain (45 - 192)

C8

C8: C8 domain (227 - 298)

TIL

TIL: Trypsin Inhibitor like cysteine rich domain (302 - 357)

VWD

VWD: von Willebrand factor type D domain (397 - 549)

C8

C8: C8 domain (588 - 660)

TIL

TIL: Trypsin Inhibitor like cysteine rich domain (664 - 721)

TIL

TIL: Trypsin Inhibitor like cysteine rich domain (764 - 827)

VWD

VWD: von Willebrand factor type D domain (868 - 1017)

C8

C8: C8 domain (1055 - 1128)

  • 0
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  • 2000
  • 2439 a.a.
Protein Preferred Names Protein Names

mucin-6

  • gastric mucin-6

MUC6 Antibodies

Cat. No. Product Name Application Reactivity
HY-P80989 MUC6 Antibody (YA3514) IHC-P Human
HY-P85975 MUC6 Antibody (YA5667) IHC-P, ICC/IF, ELISA Human
HY-P86041 MUC6 Antibody (YA5733) IHC-P, ICC/IF, ELISA Human

Related Diseases

Diseases Alias
Pancreatic Ductal Carcinoma

  • Carcinoma, Pancreatic Ductal

  • Malignant Neoplasm Of Duct Of Wirsung

  • Pancreatic Duct Cancer

  • Carcinoma Pancreatic Ductal
Barrett Esophagus

  • Barrett'S Esophagus

  • Barrett Esophagus/Esophageal Adenocarcinoma

  • Barrett Metaplasia

  • Barrett'S Ulcer Of Esophagus

  • Ulcerative Esophagitis

  • Barrett'S Esophagus With Esophagitis

  • Barrett'S Oesophagus

  • Barretts Syndrome

  • Barrett Syndrome

  • BE

  • Peptic Ulcer Of Esophagus

  • Adenocarcinoma Of Esophagus
Cervical Mucinous Adenocarcinoma
Pancreatic Serous Cystic Neoplasm

  • Pancreatic Serous Neoplasm
Bronchiolo-Alveolar Adenocarcinoma

  • Bronchioloalveolar Carcinoma

  • Bronchioalveolar Lung Carcinoma

  • Minimally Invasive Lung Adenocarcinoma

  • Carcinoma Bronchioloalveolar

  • Adenocarcinoma, Bronchiolo-Alveolar

  • Bronchioloalveolar Adenocarcinoma
Pseudomyxoma Peritonei

  • Adenomucinosis

  • Gelatinous Ascites

  • Pmp

  • Mucinous Ascites

  • Syndrome Of Pseudomyxoma Peritonei
Gastritis

  • Acute Gastric Mucosal Erosion

  • Erosive Gastritis

  • Erosive Gastropathy

  • Gastritis Erosive

  • Idiopathic Erosive/Hemorrhagic Gastritis

  • Inflammation Of Gastric Mucosa

  • Gastroduodenitis

  • Gastritis Nos

  • Noninfectious Gastroenteritis

  • Nonbacterial Gastroenteritis Of Infant

  • Acute Gastric Infection

  • Acute Simple Gastritis

  • Chronic Antral Gastritis

  • Chronic Fundal Gastritis

  • Chronic Simple Gastritis

  • Acute Gastroduodenitis

  • Acute Antral Gastritis

  • Acute Erosive Gastritis

  • Bile Reflux Gastritis

  • Gastritis Due To Biliary Reflux
Biliary Tract Benign Neoplasm

  • Extrahepatic Bile Duct Neoplasm

  • Neoplasm Of Extrahepatic Bile Ducts

  • Tumor Of The Extrahepatic Bile Duct
Biliary Papillomatosis

  • Bile Duct Papillomatosis
Cystadenoma

  • Cystoma

  • Craniopharyngioma
Cholecystitis

  • Acute Cholecystitis

  • Chronic Cholecystitis

  • Acalculous Cholecystitis

  • Acute And Chronic Cholecystitis

  • Acute On Chronic Cholecystitis

  • Gallstone Cholecystitis

  • Cholecystitis, Acute

  • Calculus Of Gallbladder With Cholecystitis

  • Gallbladder Inflammation

  • Acute Cholecystitis Infection

  • Acute Acalculous Cholecystitis

  • Chronic Acalculous Cholecystitis

  • Nonfunctioning Gallbladder
Chronic Ethmoiditis

  • Chronic Ethmoidal Sinusitis

  • Chronic Ethmoid Sinusitis

  • Ethmoidal Sinusitis - Chronic
Solid Adenocarcinoma With Mucin Production
Small Intestine Cancer

  • Small Intestine Carcinoma

  • Cancer Of The Small Bowel

  • Small Bowel Cancer

  • Small Intestinal Carcinoma

  • Malignant Neoplasms Of The Small Intestine

  • Small Bowel Tumors

  • Malignant Tumor Of Small Intestine

  • Neoplasm Of Small Intestine
Ampulla Of Vater Cancer

  • Ampulla Of Vater Carcinoma

  • Ampullary Carcinoma

  • Malignant Tumour Of Ampulla Of Vater

  • Carcinoma Of Ampulla Of Vater

  • Carcinoma Of The Ampulla Of Vater

  • Ampulloma
Cervical Adenoma Malignum

  • Cervical Mucinous Adenocarcinoma, Minimal Deviation Variant
Peutz-Jeghers Syndrome

  • PJS

  • Polyposis, Hamartomatous Intestinal

  • Polyps-And-Spots Syndrome

  • Lentiginosis, Perioral

  • Periorificial Lentiginosis Syndrome

  • Hamartomatous Intestinal Polyposis

  • Hamartomatous Polyp

  • Colonic Hamartomatous Polyp

  • Gastric Peutz-Jeghers Polyp

  • Peutz Jeghers Colon Polyp

  • Peutz Jeghers Polyp

  • Peutz-Jeghers Polyp Of Small Intestine

  • Peutz-Jeghers Small Bowel Hamartoma

  • Peutz Jeghers Polyposis

  • Intestinal Polyposis-Cutaneous Pigmentation Syndrome

  • Peutz-Jeghers Polyposis

  • Polyposis, Intestinal, Ii

  • Intestinal Hamartomatous Polyposis

  • Peutz-Jeghers Polyp

  • Peutz-Jeghers Polyp Of The Stomach

  • Peutz Jehgers Polyp

  • Peutz-Jeghers Polyps Of Small Bowel
Microcystic Adenoma

  • Adenoma Microcystic

  • Adenoma, Microcystic
Adenoma

  • Acinar Cell Adenoma

  • Adenomas

  • Acinic Cell Adenoma
Mucinous Tubular And Spindle Renal Cell Carcinoma

  • Mucinous Tubular And Spindle Cell Renal Carcinoma
Duodenum Adenocarcinoma

  • Duodenal Adenocarcinoma
Bile Duct Cancer

  • Bile Duct Carcinoma

  • Extrahepatic Bile Duct Carcinoma

  • Carcinoma Of Extrahepatic Bile Duct

  • Extrahepatic Bile Duct Cancer

  • Bile Duct Neoplasms

  • Bile Duct Tumor

  • Ca Extrahepatic Bile Ducts

  • Malignant Neoplasm Of The Extrahepatic Bile Duct

  • Bile Duct Extrahepatic Carcinoma

  • Malignant Tumor Of Extrahepatic Bile Duct
Gastric Tubular Adenocarcinoma

  • Tubular Adenocarcinoma Of Stomach
Small Intestine Adenocarcinoma

  • Small Intestinal Adenocarcinoma

  • Adenocarcinoma Of Small Intestine

  • Adenocarcinoma Of The Small Bowel

  • Adenocarcinoma Of Small Bowel

  • Adenocarcinoma Of Small Instestine

  • Adenocarcinoma Of The Small Instestine

  • Small Bowel Adenocarcinoma

  • Adenocarcinoma Of The Small Intestine
Gastric Cancer

  • Stomach Cancer

  • Gastric Carcinoma

  • Stomach Carcinoma

  • Gastric Cancer, Somatic

  • Gastric Neoplasm

  • Carcinoma Of Stomach

  • Stomach Neoplasms

  • Malignant Neoplasm Of Stomach

  • Gastric Cancer Risk After H. Pylori Infection

  • Cancer Of The Stomach

  • Adult Stomach Cancer

  • Adult Stomach Carcinoma

  • GASC

  • Gastric Cancer Intestinal

  • Gastric Cancers

  • Gastric Carcinomas

  • Cancer, Gastric

  • Stomach Neoplasm

  • Malignant Neoplasm Of Body Of Stomach

  • Malignant Tumor Of Lesser Curve Of Stomach

  • Gastrocarcinoma Of Unspecified Site

  • Leather Bottle Stomach

  • Carcinoma Of Fundus Of Stomach

  • Cancer Of Fundus Of Stomach

  • Primary Malignant Neoplasm Of Body Of Stomach

  • Cancer Of Body Of Stomach

  • Primary Malignant Neoplasm Of Pyloric Antrum

  • Pyloric Antrum Cancer

  • Malignant Tumour Of Stomach
Mucinous Adenocarcinoma

  • Mucin-Producing Adenocarcinoma

  • Mucin-Secreting Adenocarcinoma

  • Mucin-Secreting Carcinoma

  • Mucous Carcinoma

  • Pseudomyxoma Peritonei With Unknown Primary Site

  • Adenocarcinoma, Mucinous
Urinary Bladder Villous Adenoma

  • Villous Adenoma Of Urinary Bladder

  • Bladder Villous Adenoma
Bile Duct Cystadenocarcinoma

  • Biliary Cystadenocarcinoma

  • Intrahepatic Bile Duct Cystadenocarcinoma

  • Intrahepatic Bile Duct Mucinous Cystic Neoplasm With An Associated Invasive Carcinoma
Signet Ring Cell Adenocarcinoma

  • Signet Ring Cell Carcinoma

  • Carcinoma, Signet Ring Cell

  • Signet Ring Carcinoma

  • Carcinoma Signet Ring Cell
Polyposis Syndrome, Hereditary Mixed, 1

  • HMPS1

  • Colorectal Adenoma And Carcinoma 1

  • Crac1

  • Colorectal Cancer 4

  • Chromosome 15q13-Q14 Duplication Syndrome, 40-Kb

  • Colorectal Cancer, Susceptibility To, 4

  • Hereditary Mixed Polyposis Syndrome 1

  • Polyposis Syndrome, Hereditary Mixed 1

  • CRCS4

  • Susceptibility To Colorectal Cancer On Chromosome 15

  • Polyposis Syndrome, Mixed Hereditary 1

  • Adenomatous Polyps
Pancreatic Serous Cystadenoma
Ovarian Mucinous Neoplasm

  • Ovarian Mucinous Tumor

  • Malignant Ovarian Mucinous Neoplasm

  • Mucinous Tumor Of Ovary

  • Malignant Ovarian Mucinous Tumor
Mucinous Cystadenocarcinoma Of Pancreas

  • Pancreatic Mucinous Cystadenocarcinoma

  • Mucinous Cystadenocarcinoma Of The Pancreas

  • Pancreatic Colloid Cystadenocarcinoma
Autoimmune Gastritis
Bile Duct Adenoma

  • Cholangioadenoma

  • Adenoma Bile Duct

  • Adenoma, Bile Duct
Duodenum Cancer

  • Duodenal Cancer

  • Duodenal Neoplasms

  • Cancer Of Duodenum

  • Duodenal Neoplasm

  • Duodenal Carcinoma

  • Cancer, Duodenal

  • Malignant Neoplasm Of Duodenum
Appendix Cancer

  • Appendiceal Neoplasms

  • Cancer Of The Appendix

  • Malignant Neoplasm Of Appendix Vermiformis

  • Malignant Tumor Of Appendix

  • Malignant Tumor Of The Appendix

  • Malignant Neoplasm Of Appendix

  • Carcinoma Of The Appendix
Appendix Disease

  • Disorder Of Appendix
Endocervical Carcinoma

  • Carcinoma Of Endocervix

  • Carcinoma Of The Endocervix
Gallbladder Carcinoma In Situ
Villous Adenoma

  • Adenoma Villous

  • Adenoma, Villous
Gastritis, Familial Giant Hypertrophic

  • Menetrier Disease

  • Gastric Mucosal Hypertrophy

  • Giant Hypertrophic Gastritis

  • Hypertrophic Gastropathy

  • Gastritis, Hypertrophic

  • Familial Giant Hypertrophic Gastritis

  • Giant Rugal Hypertrophy Of Stomach

  • Hypertrophic Gastritis

  • Gastroenteropathy, Protein Losing

  • Giant Hypertrophic Gastropathy

  • Giant Hypertrophy Of The Gastric Mucosa

  • Hypoproteinemic Hypertrophic Gastropathy

  • Menetrier'S Disease

  • Giant Hypertrophic Hypersecretory Gastritis
Mucinous Intrahepatic Cholangiocarcinoma

  • Mucin-Producing Intrahepatic Cholangiocarcinoma
Pancreatic Signet Ring Cell Adenocarcinoma

  • Pancreatic Signet Ring Cell Carcinoma

  • Signet Ring Cell Carcinoma Of Pancreas
Gallbladder Adenocarcinoma

  • Adenocarcinoma Of The Gallbladder

  • Carcinoma Of The Gallbladder
Papillary Adenofibroma
Duodenum Disease

  • Duodenal Diseases

  • Duodenal Disease

  • Duodenum Disorder
Adenocarcinoma In Situ
Tubular Adenocarcinoma

  • Tubular Carcinoma

  • Adenocarcinoma Tubular

  • Adenocarcinoma, Tubular
Ampulla Of Vater Adenocarcinoma

  • Adenocarcinoma Of Ampulla Of Vater

  • Ampullary Adenocarcinoma
Hepatoid Adenocarcinoma
Microinvasive Gastric Cancer

  • Early Gastric Cancer

  • Surface Gastric Cancer
Pancreatic Cystadenocarcinoma

  • Cystadenocarcinoma Of Pancreas
Cystic Fibrosis

  • Mucoviscidosis

  • CF

  • Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis

  • Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis

  • Cystic Fibrosis Lung Disease, Modifier Of

  • Cystic Fibrosis Of Pancreas

  • Fibrocystic Disease Of Pancreas

  • Cf - [Cystic Fibrosis]

  • Cystic Fibrosis Nos

  • Fibrocystic Disease

  • Fibrocystic Disease Of The Pancreas

  • Mucoviscidosis Of Pancreas

  • Nonproliferative Fibrocystic Disease

  • Pancreatic Cystic Fibrosis
Barrett'S Adenocarcinoma

  • Barrett Adenocarcinoma

  • Adenocarcinoma Arising In Barrett'S Mucosa
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Gallbladder Benign Neoplasm
Endocervical Adenocarcinoma

  • Endocervical Carcinoma
Cervical Polyp

  • Cervix Adenomatous Polyp
Acute Cholangitis
Colorectal Cancer

  • Colon Cancer

  • Colorectal Carcinoma

  • Colon Carcinoma

  • Colorectal Cancer, Susceptibility To

  • Carcinoma Of Colon

  • CRC

  • Colorectal Cancer With Chromosomal Instability, Somatic

  • Colon Cancer, Somatic

  • Colon Cancer, Susceptibility To

  • Colonic Neoplasms

  • Colorectal Neoplasms

  • Colorectal Cancer, Somatic

  • Colon Cancer, Advanced, Somatic

  • Colonic Carcinoma

  • Colorectal Carcinomas

  • Colon Cancers

  • Colorectal Cancers

  • Cancer, Colorectal, Somatic

  • Cancer, Colon

  • Cancer, Colorectal, Susceptibility To

  • Colorectal Neoplasm

  • Colonic Neoplasm

  • Malignant Tumor Of Colon
Gastric Teratoma

  • Teratoma Of Stomach
Gallbladder Cancer

  • Gallbladder Carcinoma

  • Gallbladder Neoplasm

  • Malignant Neoplasm Of Gallbladder

  • Malignant Tumour Of Gallbladder

  • Gallbladder Ca

  • Localized Malignant Gallbladder Neoplasm

  • Malignant Tumor Of The Gallbladder

  • Tumor Of The Gallbladder

  • Cancer Of The Gallbladder

  • Carcinoma Gallbladder

  • Carcinoma Of Gallbladder

  • Gallbladder Neoplasms

  • Malignant Neoplasm Of Gallbladder Localized

  • Cancer Of Gallbladder

  • Primary Malignant Neoplasm Of Gallbladder
Ovarian Cystadenocarcinoma

  • Cystadenocarcinoma Of Ovary

  • Cystadenocarcinoma Of The Ovary
Diffuse Gastric And Lobular Breast Cancer Syndrome

  • Hereditary Diffuse Gastric Cancer

  • HDGC

  • LBC

  • Familial Diffuse Gastric Cancer

  • Fdgc

  • Hereditary Diffuse Gastric Adenocarcinoma

  • Breast Cancer, Lobular

  • Gastric Cancer, Familial Diffuse, And Cleft Lip With Or Without Cleft Palate

  • DGLBC

  • Gastric Cancer, Hereditary Diffuse

  • Gastric Cancer, Familial Diffuse Breast Cancer, Lobular

  • Diffuse Gastric And Lobular Breast Cancer Syndrome With Or Without Cleft Lip And/Or Palate

  • E-Cadherin-Associated Hereditary Gastric Cancer

  • Familial Diffuse Cancer Of Stomach

  • Hereditary Diffuse Cancer Of Stomach

  • Gastric Cancer Familial Diffuse

  • Gastric Cancer Familial Diffuse And Cleft Lip With Or Without Cleft Palate

  • Cancer, Gastric, Hereditary Diffuse
Cervix Carcinoma

  • Cancer Of Cervix

  • Carcinoma Of Cervix

  • Carcinoma Cervix Uteri

  • Carcinoma Of The Cervix Uteri
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08846 MUC6 Human Pre-designed siRNA Set A / Unkown
HY-RS20777 Muc6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27291 Muc6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus MUC6 MGD MGI:2663233
Rattus norvegicus MUC6 RGD RGD:628826
Others MUC6 NCBI