MUC6 Antibody (YA3514)

製品番号: HY-P80989: データシート User Guide for Antibodies
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MUC6 Antibody (YA3514) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUC6.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
20 μL	$183	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	$276	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	$432	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

Synthetic products have potential research and development risk.

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* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

MUC6 Antibody (YA3514) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUC6.

Host

Mouse

Clonality

Monoclonal

Species Reactivity

Human

SwissProt ID

Q6W4X9

Gene ID

4588 [NCBI]

Immunogen

Synthesized peptide derived from human MUC6

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:500

Sensitivity	Endogenous	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Background

Function：May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis

Subcellular Localization：Secreted

Expression：
Tissue_specificity:It is expressed in the regeneration zone of the gastric antrum, the mucosa of the gastric body, and the mucosa of the gastric notch. It is also expressed in the deep mucous glands of the gastric antrum. It is overexpressed in gastric epithelium infected with Helicobacter pylori. It is highly expressed in the Brenner's glands of the duodenum, gallbladder, seminal vesicle, central cells and ducts of the pancreatic acinar, and glands surrounding the common bile duct.

Induction:Up-regulated by NFKB1. Repressed by mithramycin A which is an inhibitor of binding of transcription factors

Subunit：Multimer; disulfide-linked

Database

Entrez Gene: 4588 Human

SwissProt: Q6W4X9 Human

OMIM: 158374 Human

Research Field

Signal Transduction

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/k562-cell.html [Content Brief]