MUC6 Antibody (YA5667)

Cat. No.: HY-P85975: Data Sheet COA
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User Guide for Antibodies
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MUC6 Antibody (YA5667) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUC6.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

MUC6 Antibody (YA5667) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUC6.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 257 kDa;

Species Reactivity

Human

SwissProt ID

Q6W4X9

Gene ID

4588 [NCBI]

Immunogen

Synthesized peptide derived from human MUC6 AA range: 1000-1100

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-400
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-200
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:500-5000

Purity	affinity chromatography.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG2a,IgG/Kappa

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis

Subcellular Localization：Secreted

Expression：
Tissue_specificity:It is expressed in the regeneration zone of the gastric antrum, the mucosa of the gastric body, and the mucosa of the gastric notch. It is also expressed in the deep mucous glands of the gastric antrum. It is overexpressed in gastric epithelium infected with Helicobacter pylori. It is highly expressed in the Brenner's glands of the duodenum, gallbladder, seminal vesicle, central cells and ducts of the pancreatic acinar, and glands surrounding the common bile duct.

Induction:Up-regulated by NFKB1. Repressed by mithramycin A which is an inhibitor of binding of transcription factors

Subunit：Multimer; disulfide-linked

Synonyms

Gastric mucin 6; Gastric Mucin; Gastric mucin-6; MUC 6; MUC-6; Muc6; MUC6 Fragment; MUC6 mucin; MUC6 mucin Fragment; MUC6_HUMAN; Mucin 6; Mucin 6 gastric; Mucin 6 oligomeric mucus/gel forming; Mucin glycoprotein Fragment; Mucin-6; Secretory mucin MUC6 Fragment

Documentation

Select Batch:

Data Sheet (233 KB) SDS (252 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)