Atp2a3 - ATPase, Ca++ transporting, ubiquitous Gene

Also Known as Serca3; SERCA3b

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53313

Summary

Enables calcium ion binding activity. Predicted to be involved in several processes, including activation of cysteine-type endopeptidase activity involved in apoptotic process; calcium ion transport from cytosol to endoplasmic reticulum; and intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to act upstream of or within calcium ion transport. Located in endoplasmic reticulum. Orthologous to human ATP2A3 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3). [provided by Alliance of Genome Resources, Apr 2022]

Atp2a3 Products (3)

mRNA Protein Name
NM_001163336.1 NP_001156808.1 sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform a
NM_001163337.1 NP_001156809.1 sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform c
NM_016745.3 NP_058025.2 sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform b

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25640239 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
12119294 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sarcoplasmic/endoplasmic reticulum calcium ATPase 3

  • SR Ca(2+)-ATPase 3

  • calcium pump 3

  • sarco /endoplasmic reticulum Ca2+ -ATPase

  • sarcoendoplasmic reticulum Ca2+ ATPase type 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01193 ATP2A3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01196 ATP2B3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp2a3 NCBI NCBI:489