Caprin1 - cell cycle associated protein 1 Gene

Also Known as P137; Gpiap; Gpiap1; rng105; Caprin-1; Mmgpip137

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53872

Summary

Predicted to enable RNA binding activity. Involved in positive regulation of dendritic spine morphogenesis. Located in cytoplasmic stress granule and synapse. Is expressed in central nervous system; eye; and male reproductive system. Orthologous to human CAPRIN1 (cell cycle associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Caprin1 Products (15)

mRNA Protein Name
NM_001111289.2 NP_001104759.1 caprin-1 isoform a
NM_001111290.2 NP_001104760.1 caprin-1 isoform b
NM_001111291.2 NP_001104761.1 caprin-1 isoform c
NM_001111292.2 NP_001104762.1 caprin-1 isoform c
NM_001412568.1 NP_001399497.1 caprin-1 isoform d
NM_001412569.1 NP_001399498.1 caprin-1 isoform d
NM_001412570.1 NP_001399499.1 caprin-1 isoform e
NM_001412571.1 NP_001399500.1 caprin-1 isoform e
NM_001412572.1 NP_001399501.1 caprin-1 isoform b
NM_001412574.1 NP_001399503.1 caprin-1 isoform f
NM_001412575.1 NP_001399504.1 caprin-1 isoform g
NM_001412576.1 NP_001399505.1 caprin-1 isoform h
NM_001412577.1 NP_001399506.1 caprin-1 isoform i
NM_001412578.1 NP_001399507.1 caprin-1 isoform i
NM_016739.4 NP_058019.2 caprin-1 isoform a

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within generation of neurons IMP
IMP: Inferred from mutant phenotype
20861386 MGI
acts upstream of or within intracellular mRNA localization IMP
IMP: Inferred from mutant phenotype
20861386 MGI
acts upstream of or within nervous system development IMP
IMP: Inferred from mutant phenotype
20861386 MGI
involved in positive regulation of dendrite morphogenesis IMP
IMP: Inferred from mutant phenotype
20516077 MGI
involved in positive regulation of dendritic spine morphogenesis IMP
IMP: Inferred from mutant phenotype
20516077 MGI
acts upstream of or within synapse assembly IMP
IMP: Inferred from mutant phenotype
20861386 MGI
acts upstream of or within synapse organization IMP
IMP: Inferred from mutant phenotype
20861386 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasmic stress granule IDA
IDA: Inferred from direct assay
21933836 MGI
is active in dendrite IMP
IMP: Inferred from mutant phenotype
20861386 MGI
is active in synapse EXP
EXP: Inferred from Experiment
16452087 MGI
is active in synapse IDA
IDA: Inferred from direct assay
16452087 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

caprin-1

  • GPI-anchored membrane protein 1

  • GPI-anchored protein p137

  • GPI-p137

  • RNA granule protein 105

  • cytoplasmic activation- and proliferation-associated protein 1

  • cytoplasmic activation/proliferation-associated protein 1

  • membrane component chromosome 11 surf

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-162288 FAZ-3532 Inhibitor 99.66% Unkown
HY-162289 FAZ-3780 99.68% Unkown
HY-161110 APP degrader-1 Degrader 99.11% Unkown
HY-RS01897 CAPRIN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-165042 1,2-Dipalmitoyl-3-decanoyl-rac-glycerol / Unkown
HY-165105 1,3-Dioleoyl-2-decanoyl glycerol / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Caprin1 NCBI NCBI:4076