Barhl1 - BarH like homeobox 1 Gene

Also Known as MBH2; Dres115

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54422

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Acts upstream of or within several processes, including negative regulation of neuron apoptotic process; nervous system development; and sensory perception of sound. Located in nucleus. Is expressed in several structures, including central nervous system; ear; future brain; heart; and urinary system. Orthologous to human BARHL1 (BarH like homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Barhl1 Products (4)

mRNA Protein Name
NM_001164186.1 NP_001157658.1 barH-like 1 homeobox protein isoform a
NM_001355434.1 NP_001342363.1 barH-like 1 homeobox protein isoform a
NM_001355435.1 NP_001342364.1 barH-like 1 homeobox protein isoform b
NM_019446.4 NP_062319.1 barH-like 1 homeobox protein isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
18212062 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within midbrain development IMP
IMP: Inferred from mutant phenotype
16752387 MGI
acts upstream of or within negative regulation of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
12091321 MGI
acts upstream of or within negative regulation of outer hair cell apoptotic process IMP
IMP: Inferred from mutant phenotype
12091321 MGI
acts upstream of neuron apoptotic process IMP
IMP: Inferred from mutant phenotype
12091321 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
15044550 MGI
acts upstream of outer hair cell apoptotic process IMP
IMP: Inferred from mutant phenotype
12091321 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
18212062 MGI
acts upstream of or within sensory perception of sound IMP
IMP: Inferred from mutant phenotype
12091321 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
18212062 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

barH-like 1 homeobox protein

  • bar-class homeodomain protein MBH2

  • barH-related homeobox protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01366 BARHL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Barhl1 NCBI NCBI:56751