EPDR1 - ependymin related 1 Gene

Homo sapiens

Also known as EPDR; UCC1; MERP1; MERP-1

Gene ID: 54749 | Gene type: protein coding

About EPDR1

Cytogenetic location: 7p14.1 Genomic coordinates (GRCh38): 7:37,920,640-37,951,936 (from NCBI)

This gene has 3 transcripts (splice variants) and 489 orthologues. Broad expression in brain (RPKM 25.1), endometrium (RPKM 24.9) and 23 other tissues.

Summary

The protein encoded by this gene is a type II transmembrane protein that is similar to two families of cell adhesion molecules, the protocadherins and ependymins. This protein may play a role in calcium-dependent cell adhesion. This protein is glycosylated, and the orthologous mouse protein is localized to the lysosome. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8. [provided by RefSeq, Aug 2011]

EPDR1 Products(3)

mRNA	Protein	Name
NM_001242946.2	NP_001229875.2	mammalian ependymin-related protein 1 isoform 2 precursor
NM_001242948.2	NP_001229877.1	mammalian ependymin-related protein 1 isoform 3
NM_017549.5	NP_060019.2	mammalian ependymin-related protein 1 isoform 1 precursor

EPDR1 Protein Structure

Ependymin

0
100
200
224 a.a.

Protein Preferred Names

Protein Names

mammalian ependymin-related protein 1

ependymin related protein 1

Recombinant EPDR1 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70935	EPDR1 Protein, Human (186a.a, HEK293, His)	Q9UM22 (A38-S223)	≥95%
HY-P76318	EPDR1 Protein, Human (224a.a, HEK293, His)	Q9UM22 (M1-W224)	≥95%

Related Diseases

Diseases

Alias

Primary Angle-Closure Glaucoma

Primary Angle Closure Glaucoma	Angle Closure Glaucoma
Acg - [Angle Closure Glaucoma]	Angle-Closure Glaucoma
Closed Angle Glaucoma	Acute Glaucoma
Prodromal Angle Closure Glaucoma

Eastern Equine Encephalitis

Eee	Neuroinvasive Eastern Equine Encephalitis Virus Infection
Eastern Equine Encephalomyelitis	Encephalomyelitis, Eastern Equine
Triple E	Eastern Equine Encephalitis Virus Infection
Neuroinvasive Eastern Equine Encephalitis Virus Disease	Eee - [Eastern Equine Encephalitis]

Colorectal Cancer

Colon Cancer	Colorectal Carcinoma
Colon Carcinoma	Colorectal Cancer, Susceptibility To
Carcinoma Of Colon	CRC
Colorectal Cancer With Chromosomal Instability, Somatic	Colon Cancer, Somatic
Colon Cancer, Susceptibility To	Colonic Neoplasms
Colorectal Neoplasms	Colorectal Cancer, Somatic
Colon Cancer, Advanced, Somatic	Colonic Carcinoma
Colorectal Carcinomas	Colon Cancers
Colorectal Cancers	Cancer, Colorectal, Somatic
Cancer, Colon	Cancer, Colorectal, Susceptibility To
Colorectal Neoplasm	Colonic Neoplasm
Malignant Tumor Of Colon

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04421	EPDR1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	EPDR1	MGD	MGI:2145369
Bos taurus	EPDR1	VGNC	VGNC:28530
Canis familiaris	EPDR1	VGNC	VGNC:51868
Macaca mulatta	EPDR1	VGNC	VGNC:108399
Rattus norvegicus	EPDR1	RGD	RGD:1359161
Others	EPDR1	NCBI

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