PM20D2 - peptidase M20 domain containing 2 Gene

Also Known as ACY1L2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 135293

Summary

Enables dipeptidase activity and identical protein binding activity. Acts upstream of or within proteolysis and regulation of protein metabolic process. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Ubiquitous expression in prostate (RPKM 11.9), ovary (RPKM 8.1) and 25 other tissues.

PM20D2 Products (1)

mRNA Protein Name
NM_001010853.3 NP_001010853.1 xaa-Arg dipeptidase

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables dipeptidase activity IDA
IDA: Inferred from direct assay
24891507 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
Biological Process GO Annotation Evidence References Source
acts upstream of or within proteolysis IDA
IDA: Inferred from direct assay
24891507 GOA
acts upstream of or within regulation of protein metabolic process IDA
IDA: Inferred from direct assay
24891507 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

PM20D2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
PM20D2 Q8IYS1 DNAJC11 Homo sapiens Q9NVH1
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 REL Homo sapiens Q04864-2
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 REL Homo sapiens Q04864-2
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 CERT1 Homo sapiens Q9Y5P4-2
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 CERT1 Homo sapiens Q9Y5P4-2
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 CERT1 Homo sapiens Q9Y5P4-2
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 KRTAP26-1 Homo sapiens Q6PEX3
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 CNNM3 Homo sapiens Q8NE01
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 KRTAP26-1 Homo sapiens Q6PEX3
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 HAPLN2 Homo sapiens Q9GZV7
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 TAPBPL Homo sapiens Q9BX59
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 POU6F2 Homo sapiens P78424
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 POU6F2 Homo sapiens P78424
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 NAA80 Homo sapiens Q93015-2
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 SIVA1 Homo sapiens O15304-2
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 SIVA1 Homo sapiens O15304-2
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 MEOX1 Homo sapiens P50221
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 MEOX1 Homo sapiens P50221
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 KRT75 Homo sapiens O95678
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 KRT75 Homo sapiens O95678
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 PSMA1 Homo sapiens P25786
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 PSMA1 Homo sapiens P25786
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 SAXO1 Homo sapiens Q8IYX7
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 SAXO1 Homo sapiens Q8IYX7
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 SAXO1 Homo sapiens Q8IYX7
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 MYOZ3 Homo sapiens Q8TDC0
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 MYOZ3 Homo sapiens Q8TDC0
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 MYOZ3 Homo sapiens Q8TDC0
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 RUSC1 Homo sapiens Q9BVN2
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 RUSC1 Homo sapiens Q9BVN2
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 RUSC1 Homo sapiens Q9BVN2
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 RGS12 Homo sapiens O14924
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 RGS12 Homo sapiens O14924
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 DDIT4L Homo sapiens Q96D03
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 DDIT4L Homo sapiens Q96D03
Validated Y2H
32296183
Intra
PM20D2 Q8IYS1 DDIT4L Homo sapiens Q96D03
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 TDO2 Homo sapiens P48775
Y2H Array
32296183
Intra
PM20D2 Q8IYS1 TDO2 Homo sapiens P48775
Y2H Prey Pooling
32296183
Intra
PM20D2 Q8IYS1 EPDR1 Homo sapiens Q9UM22
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10757 PM20D1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown