BTG4 - BTG anti-proliferation factor 4 Gene

Also Known as PC3B; APRO3; OOMD8

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 54766

About BTG4

Cytogenetic location: 11q23.1 Genomic coordinates (GRCh38): 11:111,383,826-111,514,725 (from NCBI)

This gene has 5 transcripts (splice variants), 194 orthologues, 3 paralogues and is associated with 1 phenotype. Restricted expression toward testis (RPKM 4.9).

Summary

The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein can induce G1 arrest in the cell cycle. [provided by RefSeq, Jul 2008]

BTG4 Products (4)

mRNA Protein Name
NM_001367974.1 NP_001354903.1 protein BTG4 isoform 2
NM_001367975.1 NP_001354904.1 protein BTG4 isoform 2
NM_001367976.1 NP_001354905.1 protein BTG4 isoform 3
NM_017589.4 NP_060059.1 protein BTG4 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32502391 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

BTG4 Protein Structure

BTG

BTG: BTG family (1 - 117)

  • 0
  • 100
  • 200
  • 223 a.a.
Protein Preferred Names Protein Names

protein BTG4

  • B-cell translocation gene 4

Related Diseases

Diseases Alias
Oocyte Maturation Defect 8

  • OOMD8
Infertility
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01665 BTG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus BTG4 MGD MGI:1860140
Canis familiaris BTG4 VGNC VGNC:53306
Felis catus BTG4 VGNC VGNC:81909
Bos taurus BTG4 VGNC VGNC:26600
Rattus norvegicus BTG4 RGD RGD:1308809
Macaca mulatta BTG4 VGNC VGNC:70305
Others BTG4 NCBI