ACSM5 - acyl-CoA synthetase medium chain family member 5 Gene

Homo sapiens

Gene ID: 54988 | Gene type: protein coding

About ACSM5

Cytogenetic location: 16p12.3 Genomic coordinates (GRCh38): 16:20,409,534-20,441,336 (from NCBI)

This gene has 7 transcripts (splice variants), 221 orthologues and 13 paralogues. Biased expression in liver (RPKM 53.9), fat (RPKM 14.6) and 1 other tissue.

Summary

Predicted to enable fatty acid ligase activity and fatty-acyl-CoA synthase activity. Predicted to be involved in acyl-CoA metabolic process and fatty acid biosynthetic process. Predicted to be active in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

ACSM5 Products(4)

mRNA	Protein	Name
NM_001324371.2	NP_001311300.1	acyl-coenzyme A synthetase ACSM5, mitochondrial isoform 1
NM_001324372.2	NP_001311301.1	acyl-coenzyme A synthetase ACSM5, mitochondrial isoform 2
NM_001324373.2	NP_001311302.1	acyl-coenzyme A synthetase ACSM5, mitochondrial isoform 3
NM_017888.3	NP_060358.2	acyl-coenzyme A synthetase ACSM5, mitochondrial isoform 1

ACSM5 Protein Structure

AMP-binding

AMP-binding_C

0
100
200
300
400
500
579 a.a.

Protein Preferred Names

Protein Names

acyl-coenzyme A synthetase ACSM5, mitochondrial

Related Diseases

Diseases

Alias

Spondylometaphyseal Dysplasia, Corner Fracture Type

SMDCF	Spondylometaphyseal Dysplasia, Sutcliffe Type
Spondylometaphyseal Dysplasia Corner Fracture Type	Spondylometaphyseal Dysplasia, 'Corner Fracture' Type
Spondylometaphyseal Dysplasia Sutcliffe Type	Sutcliffe Type Of Spondylometaphyseal Dysplasia
Spondylometaphyseal Dysplasia - Sutcliffe Type	Smd, Corner Fractures Type
Smd, Sutcliffe Type	Sutcliffe Smd
Dysplasia, Spondylometaphyseal, Corner Fracture Type

Arthrogryposis Multiplex Congenita-3

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS00209	ACSM5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ACSM5	MGD	MGI:2444086
Bos taurus	ACSM5	VGNC	VGNC:25569
Felis catus	ACSM5	VGNC	VGNC:59539
Canis familiaris	ACSM5	VGNC	VGNC:37536
Macaca mulatta	ACSM5	VGNC	VGNC:69535
Rattus norvegicus	ACSM5	RGD	RGD:1309578

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