Ift20 - intraflagellar transport 20 Gene

Also Known as mIFT20; 0610009H04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 55978

Summary

Enables opsin binding activity. Involved in several processes, including protein localization to ciliary membrane; regulation of organelle assembly; and regulation of platelet-derived growth factor receptor-alpha signaling pathway. Acts upstream of or within several processes, including animal organ development; morphogenesis of a polarized epithelium; and plasma membrane bounded cell projection organization. Located in several cellular components, including ciliary base; microtubule organizing center; and non-motile cilium. Part of intraciliary transport particle B. Orthologous to human IFT20 (intraflagellar transport 20). [provided by Alliance of Genome Resources, Apr 2022]

Ift20 Products (2)

mRNA Protein Name
NM_018854.5 NP_061342.1 intraflagellar transport protein 20 homolog
NM_018854.5 NP_061342.1 intraflagellar transport protein 20 homolog

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables opsin binding IPI
IPI: Inferred from physical interaction
21307337 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
12821668 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cardiac muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
19654211 MGI
acts upstream of or within centrosome localization IMP
IMP: Inferred from mutant phenotype
18981227 MGI
acts upstream of or within cilium assembly IMP
IMP: Inferred from mutant phenotype
18981227 MGI
acts upstream of or within cochlea development IMP
IMP: Inferred from mutant phenotype
25605782 MGI
acts upstream of or within establishment of epithelial cell apical/basal polarity IMP
IMP: Inferred from mutant phenotype
25605782 MGI
acts upstream of or within establishment of planar polarity IMP
IMP: Inferred from mutant phenotype
25605782 MGI
acts upstream of or within inner ear receptor cell stereocilium organization IMP
IMP: Inferred from mutant phenotype
25605782 MGI
acts upstream of or within intraciliary transport IMP
IMP: Inferred from mutant phenotype
24619649 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
18981227 MGI
acts upstream of or within neural precursor cell proliferation IMP
IMP: Inferred from mutant phenotype
21734285 MGI
acts upstream of or within neurogenesis IMP
IMP: Inferred from mutant phenotype
21734285 MGI
acts upstream of or within opsin transport IMP
IMP: Inferred from mutant phenotype
21307337 MGI
acts upstream of or within photoreceptor cell outer segment organization IMP
IMP: Inferred from mutant phenotype
21307337 MGI
acts upstream of or within protein localization to cilium IMP
IMP: Inferred from mutant phenotype
21307337 MGI
acts upstream of or within protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
25605782 MGI
acts upstream of or within protein transmembrane transport IMP
IMP: Inferred from mutant phenotype
28576874 MGI
involved in regulation of autophagosome assembly IMP
IMP: Inferred from mutant phenotype
24089209 MGI
acts upstream of or within regulation of canonical Wnt signaling pathway IMP
IMP: Inferred from mutant phenotype
18981227 MGI
involved in regulation of cilium assembly IMP
IMP: Inferred from mutant phenotype
24089209 MGI
involved in regulation of platelet-derived growth factor receptor-alpha signaling pathway IMP
IMP: Inferred from mutant phenotype
29237719 MGI
acts upstream of or within smoothened signaling pathway IMP
IMP: Inferred from mutant phenotype
19654211 MGI
acts upstream of or within spermatogenesis IMP
IMP: Inferred from mutant phenotype
31816150 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
27682589 MGI
acts upstream of or within visual learning IMP
IMP: Inferred from mutant phenotype
21734285 MGI
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
16775004 MGI
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
31816150 MGI
located in centriole IDA
IDA: Inferred from direct assay
15337773 MGI
located in centrosome IDA
IDA: Inferred from direct assay
19253336 MGI
located in ciliary basal body IDA
IDA: Inferred from direct assay
22031837 MGI
located in ciliary base IDA
IDA: Inferred from direct assay
15337773 MGI
located in cilium IDA
IDA: Inferred from direct assay
16775004 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
29690537 MGI
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
31816150 MGI
located in dendrite terminus IDA
IDA: Inferred from direct assay
20368623 MGI
part of intraciliary transport particle B IDA
IDA: Inferred from direct assay
12821668 MGI
located in kinociliary basal body IDA
IDA: Inferred from direct assay
25605782 MGI
located in manchette IDA
IDA: Inferred from direct assay
29690537 MGI
located in microvillus IDA
IDA: Inferred from direct assay
25605782 MGI
located in motile cilium IDA
IDA: Inferred from direct assay
15337773 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
25605782 MGI
located in photoreceptor connecting cilium IDA
IDA: Inferred from direct assay
21307337 MGI
located in photoreceptor outer segment IDA
IDA: Inferred from direct assay
21307337 MGI
located in stereocilium IDA
IDA: Inferred from direct assay
25605782 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

intraflagellar transport protein 20 homolog

  • intraflagellar transport 20 homolog

  • uterine protein

Ift20 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Ift20 Q61025 Atg16l1 Mus musculus Q8C0J2
Anti Bait CoIP
24089209
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11329 GFP11 98.57% Unkown
HY-RS06601 IFT20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ift20 NCBI NCBI:90410