Sec1 - secretory blood group 1 Gene

Also Known as Fut3; Fut10

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56546

Summary

This gene is one of three genes in mouse which encode a galactoside 2-L-fucosyltransferase. These genes differ in their developmental- and tissue-specific expression. This gene is predicted to encode a type II membrane protein, which is anchored in the Golgi apparatus and controls the final step in the creation of alpha (1,2) fucosylated carbhohydrates by the addition of a terminal fucose in an alpha (1,2) linkage. The biological function of the fucosylated carbhohydrate products is thought to involve cell-adhesion and interactions with Microorganisms. [provided by RefSeq, Dec 2012]

Sec1 Products (2)

mRNA Protein Name
NM_001271578.2 NP_001258507.1 galactoside 2-alpha-L-fucosyltransferase Sec1
NM_001405895.1 NP_001392824.1 galactoside 2-alpha-L-fucosyltransferase Sec1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables fucosyltransferase activity IDA
IDA: Inferred from direct assay
11323419 MGI
enables galactoside 2-alpha-L-fucosyltransferase activity IDA
IDA: Inferred from direct assay
11323419 MGI
Biological Process GO Annotation Evidence References Source
involved in oligosaccharide biosynthetic process IDA
IDA: Inferred from direct assay
11323419 MGI
acts upstream of or within protein glycosylation IDA
IDA: Inferred from direct assay
11323419 MGI
involved in protein glycosylation IDA
IDA: Inferred from direct assay
11323419 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

galactoside 2-alpha-L-fucosyltransferase Sec1

galactoside 2-alpha-L-fucosyltransferase 3

  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 3

  • GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase FUT-III

  • alpha(1,2)FT 3

  • fucosyltransferase 10