Ramp2 - receptor activity modifying protein 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 58966

Summary

Enables coreceptor activity. Involved in several processes, including female pregnancy; response to estradiol; and response to progesterone. Predicted to be located in cytoplasm. Predicted to be part of Adrenomedullin receptor complex and Amylin Receptor complex 2. Predicted to be active in cell surface. Predicted to colocalize with plasma membrane. Biomarker of adult respiratory distress syndrome; congestive heart failure; hypertension; kidney disease; and pulmonary hypertension. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human RAMP2 (receptor activity modifying protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Ramp2 Products (1)

mRNA Protein Name
NM_031646.2 NP_113834.1 receptor activity-modifying protein 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables coreceptor activity IDA
IDA: Inferred from direct assay
11556887 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
11549285 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
12801991 RGD
involved in receptor internalization IDA
IDA: Inferred from direct assay
15613468 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
15279908 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
17251392 RGD
involved in response to progesterone IEP
IEP: Inferred from expression pattern
12801991 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

receptor activity-modifying protein 2

  • receptor (G protein-coupled) activity modifying protein 2

  • receptor (calcitonin) activity modifying protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1548 β-CGRP, human 99.36% Unkown
HY-P1548A β-CGRP, human TFA 99.57% Unkown
HY-P1548B β-CGRP, human acetate / Unkown
HY-RS11639 RAMP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-183142 CLR/RAMP3-receptor antagonist-1 Antagonist / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ramp2 NCBI NCBI:10266