MGMT - O-6-methylguanine-DNA methyltransferase Gene

Species: Bos taurus

Gene Type: protein coding
Gene ID: 616091

About MGMT

Primary_assembly 26: 48,818,674-49,095,122 forward strand.ARS-UCD1.2:CM008193.2

This gene has 4 transcripts (splice variants) and 189 orthologues.

MGMT Products (5)

mRNA Protein Name
XM_024986116.1 XP_024841884.1 methylated-DNA--protein-cysteine methyltransferase isoform X2
XM_015460790.2 XP_015316276.1 methylated-DNA--protein-cysteine methyltransferase isoform X3
XM_002698584.5 XP_002698630.2 methylated-DNA--protein-cysteine methyltransferase isoform X2
XM_005225875.4 XP_005225932.1 methylated-DNA--protein-cysteine methyltransferase isoform X2
XM_024986115.1 XP_024841883.1 methylated-DNA--protein-cysteine methyltransferase isoform X1

MGMT Protein Structure

AdaB

AdaB: COG0350 (54 - 225)

  • 0
  • 100
  • 200
  • 259 a.a.
Protein Preferred Names Protein Names

methylated-DNA--protein-cysteine methyltransferase

  • 6-O-methylguanine-DNA methyltransferase

  • Methylated-DNA--protein-cysteine methyltransferase

  • O-6-methylguanine-DNA-alkyltransferase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-13668 Lomeguatrib Inhibitor 99.77% Phase 2

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13057 O6BTG-octylglucoside Inhibitor 95.0% Unkown
HY-175299 Hedgehog IN-11 Inhibitor / Unkown
HY-186228 Anticancer agent 333 / Unkown
HY-180540 MGMT-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MGMT NCBI NCBI:4255