Sptssb - serine palmitoyltransferase, small subunit B Gene

Also Known as ADMP; Sssptb; 1110032A04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 66183

Summary

Contributes to serine C-palmitoyltransferase activity. Acts upstream of or within ceramide biosynthetic process; endoplasmic reticulum organization; and regulation of serine C-palmitoyltransferase activity. Part of serine C-palmitoyltransferase complex. Is expressed in central nervous system; eye; genitourinary system; and gut. Orthologous to human SPTSSB (serine palmitoyltransferase small subunit B). [provided by Alliance of Genome Resources, Apr 2022]

Sptssb Products (3)

mRNA Protein Name
NM_001164210.2 NP_001157682.1 serine palmitoyltransferase small subunit B isoform a
NM_001286959.1 NP_001273888.1 serine palmitoyltransferase small subunit B isoform b
NM_133675.3 NP_598436.1 serine palmitoyltransferase small subunit B isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
contributes to serine C-palmitoyltransferase activity IDA
IDA: Inferred from direct assay
26438849 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
26438849 MGI
acts upstream of or within endoplasmic reticulum organization IMP
IMP: Inferred from mutant phenotype
26438849 MGI
acts upstream of or within regulation of serine C-palmitoyltransferase activity IMP
IMP: Inferred from mutant phenotype
26438849 MGI
acts upstream of or within sphingolipid biosynthetic process IMP
IMP: Inferred from mutant phenotype
26438849 MGI
Cellular Component GO Annotation Evidence References Source
part of serine palmitoyltransferase complex IDA
IDA: Inferred from direct assay
26438849 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine palmitoyltransferase small subunit B

  • androgen down regulated in mouse prostate

  • small subunit of serine palmitoyltransferase B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13740 SPTSSB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19531 Sptssb Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26026 Sptssb Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sptssb NCBI NCBI:165679