Nexn - nexilin Gene

Also Known as NELIN; 1110046H09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 68810

Summary

Predicted to enable actin filament binding activity and cell-cell adhesion mediator activity. Predicted to be a structural constituent of muscle. Acts upstream of or within response to bacterium. Predicted to be located in Z disc; actin cytoskeleton; and focal adhesion. Predicted to be active in axon and plasma membrane. Is expressed in diaphragm; gut; head mesenchyme; heart; and vertebral axis musculature. Used to study dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Orthologous to human NEXN (nexilin F-actin binding protein). [provided by Alliance of Genome Resources, Apr 2022]

Nexn Products (2)

mRNA Protein Name
NM_001357206.2 NP_001344135.1 nexilin isoform 1
NM_199465.4 NP_955759.2 nexilin isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within response to bacterium IEP
IEP: Inferred from expression pattern
23012479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nexilin

  • F-actin-binding protein

  • nF actin binding protein

  • nexilin alpha

  • nexilin beta

  • nexilin gamma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09232 NEXN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22253 Nexn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28775 Nexn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nexn NCBI NCBI:91624