2. Gene
  3. BACE2 - beta-secretase 2 Gene

BACE2 - beta-secretase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Macaca mulatta
Gene ID: 715330 | Gene type: protein coding

About BACE2

Primary_assembly 3: 5,280,196-5,481,788 reverse strand.Mmul_10:CM014338.1

This gene has 6 transcripts (splice variants), 215 orthologues and 10 paralogues.

BACE2 Products(2)

mRNA Protein Name
XM_015132852.2 XP_014988338.1 beta-secretase 2 isoform X2
XM_015132851.2 XP_014988337.1 beta-secretase 2 isoform X1

BACE2 Protein Structure

beta_secretase_like

beta_secretase_like: cd05473 (88 - 449)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 518 a.a.
Protein Preferred Names Protein Names

beta-secretase 2

beta-site APP-cleaving enzyme 2

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-16759 Verubecestat Inhibitor 99.56% Phase 3
Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-136742 BACE2-IN-1 Inhibitor 99.4% Unkown
HY-124322 NB-360 Inhibitor 99.08% Unkown
HY-12938 AMG-8718 Inhibitor / Unkown
HY-161359 BACE1-IN-14 Inhibitor / Unkown
HY-147758 BACE1/2-IN-1 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens BACE2 NCBI NCBI:25825
Mus musculus BACE2 NCBI NCBI:56175