Nfam1 - Nfat activating molecule with ITAM motif 1 Gene

Also Known as Cnaip; 4921501M20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 74039

Summary

Predicted to enable transmembrane signaling receptor activity. Involved in B cell differentiation and positive regulation of B cell receptor signaling pathway. Acts upstream of or within B cell receptor signaling pathway and regulation of B cell differentiation. Located in cell surface and membrane raft. Orthologous to human NFAM1 (NFAT activating protein with ITAM motif 1). [provided by Alliance of Genome Resources, Apr 2022]

Nfam1 Products (5)

mRNA Protein Name
NM_001271411.1 NP_001258340.1 NFAT activation molecule 1 isoform a precursor
NM_001271412.1 NP_001258341.1 NFAT activation molecule 1 isoform b
NM_001271413.1 NP_001258342.1 NFAT activation molecule 1 isoform c
NM_001271414.1 NP_001258343.1 NFAT activation molecule 1 isoform c
NM_028728.3 NP_083004.1 NFAT activation molecule 1 isoform d

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
15143214 MGI
acts upstream of or within B cell receptor signaling pathway IDA
IDA: Inferred from direct assay
15143214 MGI
involved in B cell receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
15143214 MGI
acts upstream of or within regulation of B cell differentiation IDA
IDA: Inferred from direct assay
15143214 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
15143214 MGI
located in membrane raft IDA
IDA: Inferred from direct assay
15143214 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NFAT activation molecule 1

  • calcineurin/NFAT-activating ITAM-containing protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09235 NFAM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nfam1 NCBI NCBI:150372