Kiss1r - KISS1 receptor Gene

Rattus norvegicus

Also known as Gpr54

Gene ID: 78976 | Gene type: protein coding

About Kiss1r

Primary_assembly 7: 9,785,135-9,788,793 reverse strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 135 orthologues, 14 paralogues and is associated with 14 phenotypes. Biased expression in Brain (RPKM 5.8), Testes (RPKM .9) and 1 other tissue.

Summary

Enables G protein-coupled peptide receptor activity and neuropeptide binding activity. Involved in several processes, including arachidonic acid secretion; positive regulation of cell communication; and positive regulation of stress fiber assembly. Located in membrane. Human ortholog(s) of this gene implicated in central precocious puberty 1; hypogonadism; and hypogonadotropic hypogonadism 8 with or without anosmia. Orthologous to human KISS1R (KISS1 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Kiss1r Products(2)

mRNA	Protein	Name
NM_001301151.1	NP_001288080.1	kiSS-1 receptor isoform 2
NM_023992.2	NP_076482.2	kiSS-1 receptor isoform 1

Kiss1r Protein Structure

7tmA_KiSS1R

0
100
200
300
396 a.a.

Protein Preferred Names

Protein Names

kiSS-1 receptor

G protein-coupled receptor 54	G-protein coupled receptor OT7T175
kiSS-	kiSS-1R
kisspeptins receptor	metastin receptor
orphan G protein-coupled receptor GPR54	rOT7T175

Related Agents

Clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Phase
HY-P0076A	TAK-448 acetate		98.87%	Phase 2
HY-P0076	TAK-448		/	Phase 2

Pre-clinical Phase

Bioactive Molecules (6)

Cat. No.	Product Name	Purity	Rare Diseases
HY-P2161B	TAK-683 acetate	98.97%	Unkown
HY-P2161	TAK-683	/	Unkown
HY-P2161A	TAK-683 TFA	/	Unkown
HY-RS07316	KISS1R Human Pre-designed siRNA Set A	/	Unkown
HY-RS07317	Kiss1r Mouse Pre-designed siRNA Set A	/	Unkown
HY-RS07318	Kiss1r Rat Pre-designed siRNA Set A	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Kiss1r	NCBI	NCBI:84634

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