Prkch - protein kinase C, eta Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 81749

About Prkch

Primary_assembly 6: 92,292,000-92,490,654 forward strand.mRatBN7.2:CM026979.1

This gene has 2 transcripts (splice variants), 241 orthologues, 9 paralogues and is associated with 3 phenotypes.

Summary

Enables calcium-independent protein kinase C activity. Involved in protein kinase C signaling and protein phosphorylation. Located in cytosol and membrane. Human ortholog(s) of this gene implicated in cerebral infarction. Orthologous to human PRKCH (protein kinase C eta). [provided by Alliance of Genome Resources, Apr 2022]

Prkch Products (1)

mRNA Protein Name
NM_031085.2 NP_112347.1 protein kinase C eta type

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables diacylglycerol-dependent, calcium-independent serine/threonine kinase activity IDA
IDA: Inferred from direct assay
1426252 RGD
Biological Process GO Annotation Evidence References Source
involved in protein kinase C signaling IMP
IMP: Inferred from mutant phenotype
9677361 RGD
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
1426252 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein kinase C eta type

  • PKC-L

  • nPKC-eta

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11131 PRKCH Human Pre-designed siRNA Set A / Unkown
HY-RS11132 Prkch Mouse Pre-designed siRNA Set A / Unkown
HY-RS11133 Prkch Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prkch NCBI NCBI:5583