Tfcp2l1 - transcription factor CP2-like 1 Gene

Also Known as Cp2l1; LBP-9; Crtr-1; Tcfcp2l1; 1810030F05Rik; 4932442M07Rik; D930018N21Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 81879

Summary

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including determination of adult lifespan; epithelial cell maturation; and negative regulation of transcription by RNA polymerase II. Located in cytoplasm; membrane; and nucleus. Is expressed in early conceptus; genitourinary system; heart; and limb. Orthologous to human TFCP2L1 (transcription factor CP2 like 1). [provided by Alliance of Genome Resources, Apr 2022]

Tfcp2l1 Products (1)

mRNA Protein Name
NM_023755.2 NP_076244.2 transcription factor CP2-like protein 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
20661472 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
20362541 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell morphogenesis IMP
IMP: Inferred from mutant phenotype
17079272 MGI
acts upstream of or within cytoplasm organization IMP
IMP: Inferred from mutant phenotype
17079272 MGI
acts upstream of or within determination of adult lifespan IMP
IMP: Inferred from mutant phenotype
17079272 MGI
acts upstream of or within epithelial cell maturation IMP
IMP: Inferred from mutant phenotype
17079272 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11073954 MGI
acts upstream of or within positive regulation of growth IMP
IMP: Inferred from mutant phenotype
17079272 MGI
acts upstream of or within salivary gland development IMP
IMP: Inferred from mutant phenotype
17079272 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17079272 MGI
located in membrane IDA
IDA: Inferred from direct assay
17079272 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17079272 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor CP2-like protein 1

  • CP2-related transcriptional repressor 1

  • Tcfcp2-related transcriptional repressor 1

  • transcription repressor CRTR-1

Tfcp2l1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Tfcp2l1 Q3UNW5 Esrrb Mus musculus Q61539
Anti Tag CoIP
20362541
Intra
Tfcp2l1 Q3UNW5 Esrrb Mus musculus Q61539
Pull Down
20362541
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12834A MK2-IN-1 hydrochloride Inhibitor 98.36% Unkown
HY-12834 MK2-IN-1 Inhibitor 99.04% Unkown
HY-162934 TFCP2L1-IN-1 Inducer 99.66% Unkown
HY-RS14416 TFCP2L1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tfcp2l1 NCBI NCBI:29842