TFCP2L1 - transcription factor CP2 like 1 Gene

Homo sapiens

Also known as LBP9; CRTR1; LBP-9

Gene ID: 29842 | Gene type: protein coding

About TFCP2L1

Cytogenetic location: 2q14.2 Genomic coordinates (GRCh38): 2:121,216,587-121,285,202 (from NCBI)

This gene has 2 transcripts (splice variants), 196 orthologues and 5 paralogues. Biased expression in kidney (RPKM 25.1), salivary gland (RPKM 23.9) and 10 other tissues.

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and membrane. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TFCP2L1 Products(1)

mRNA	Protein	Name
NM_014553.3	NP_055368.1	transcription factor CP2-like protein 1

TFCP2L1 Protein Structure

CP2

0
100
200
300
400
479 a.a.

Protein Preferred Names

Protein Names

transcription factor CP2-like protein 1

CP2-related transcriptional repressor 1

Related Diseases

Diseases

Alias

Chronic Kidney Disease

Chronic Renal Disease	Chronic Kidney Failure
Ckd	Chronic Renal Failure
Kidney Failure, Chronic	Chronic Renal Failure Syndrome
Crf	Renal Failure - Chronic
Renal Failure Chronic	Chronic Kidney Diseases
Chronic Kidney Disease Stage 5	Ckd - [Chronic Kidney Disease]
Crf - [Chronic Renal Failure]	Chronic Kidney Impairment
Chronic Renal Impairment	Chronic Kidney Shutdown
Chronic Hypoxic Kidney Failure	Chronic Kidney Collapse
Chronic Renal Insufficiency	Chronic Kidney Toxaemia
Chronic Kidney Hypofunction	Chronic Renal Suppression
Chronic Renal Failure, Stage 5	Ckd - [Chronic Kidney Disease] Stage 5
End Stage Kidney Failure	End Stage Renal Failure
End Stage Kidney Disease	End Stage Renal Disease
End Stage Chronic Renal Failure	Esrf - [End Stage Renal Failure]
Esrd - [End Stage Renal Diseases]	Egfr - [Estimated Glomerular Filtration Rate] < 15 Ml/Min/1.73m²

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-12834A	MK2-IN-1 hydrochloride	Inhibitor	98.96%	Unkown
HY-12834	MK2-IN-1	Inhibitor	/	Unkown
HY-RS14416	TFCP2L1 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	TFCP2L1	MGD	MGI:2444691
Bos taurus	TFCP2L1	VGNC	VGNC:35785
Felis catus	TFCP2L1	VGNC	VGNC:66114
Macaca mulatta	TFCP2L1	VGNC	VGNC:78405
Canis familiaris	TFCP2L1	VGNC	VGNC:47291
Rattus norvegicus	TFCP2L1	RGD	RGD:1305456

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