KIF2B - kinesin family member 2B Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84643

About KIF2B

Cytogenetic location: 17q22 Genomic coordinates (GRCh38): 17:53,822,927-53,825,193 (from NCBI)

This gene has 1 transcript (splice variant), 69 orthologues and 41 paralogues.

Summary

Predicted to enable microtubule binding activity and microtubule motor activity. Involved in metaphase plate congression; microtubule depolymerization; and regulation of chromosome segregation. Located in intercellular bridge; mitotic spindle; and nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

KIF2B Products (1)

mRNA Protein Name
NM_032559.5 NP_115948.4 kinesin-like protein KIF2B

KIF2B Protein Structure

Kinesin

Kinesin: Kinesin motor domain (219 - 542)

  • 0
  • 200
  • 400
  • 600
  • 673 a.a.
Protein Preferred Names Protein Names

kinesin-like protein KIF2B

  • kinesin protein

Related Diseases

Diseases Alias
Charcot-Marie-Tooth Disease

  • Cmt

  • Hmsn

  • Hereditary Motor And Sensory Neuropathy

  • Pma

  • Cmt - Charcot-Marie-Tooth Disease

  • Charcot Marie Tooth Disease

  • Charcot-Marie-Tooth Hereditary Neuropathy

  • Charcot-Marie-Tooth Syndrome

  • Peroneal Muscular Atrophy

  • Hereditary Motor And Sensory Neuropathies
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07283 KIF2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22594 Kif2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29111 Kif2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris KIF2B VGNC VGNC:55618
Macaca mulatta KIF2B VGNC VGNC:73946
Felis catus KIF2B VGNC VGNC:99093
Bos taurus KIF2B VGNC VGNC:30600
Mus musculus KIF2B MGD MGI:1920720
Rattus norvegicus KIF2B RGD RGD:1359248
Others KIF2B NCBI