Csnk1a1 - casein kinase 1, alpha 1 Gene

Also Known as CK1a; Csnk1a; 2610208K14Rik; 4632404G05Rik; 5430427P18Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 93687

Summary

Enables protein kinase activity. Involved in protein phosphorylation. Acts upstream of or within cell morphogenesis. Located in ciliary basal body. Part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; endocrine gland; metanephros; retina nuclear layer; and thymus primordium. Orthologous to several human genes including CSNK1A1 (Casein Kinase 1 alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Csnk1a1 Products (4)

mRNA Protein Name
NM_001357498.1 NP_001344427.1 casein kinase I isoform alpha isoform 2
NM_001357499.1 NP_001344428.1 casein kinase I isoform alpha isoform 3
NM_001357500.1 NP_001344429.1 casein kinase I isoform alpha isoform 4
NM_146087.3 NP_666199.1 casein kinase I isoform alpha isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein kinase activity IDA
IDA: Inferred from direct assay
21930935 MGI
enables protein serine/threonine kinase activity IDA
IDA: Inferred from direct assay
34615873 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cell morphogenesis IGI
IGI: Inferred from genetic interaction
17686994 MGI
involved in negative regulation of NLRP3 inflammasome complex assembly IDA
IDA: Inferred from direct assay
34615873 MGI
involved in protein phosphorylation IDA
IDA: Inferred from direct assay
21930935 MGI
Cellular Component GO Annotation Evidence References Source
located in ciliary basal body IDA
IDA: Inferred from direct assay
25644602 MGI
part of ribonucleoprotein complex IDA
IDA: Inferred from direct assay
21709260 MGI
located in spindle IDA
IDA: Inferred from direct assay
31338967 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

casein kinase I isoform alpha

casein kinase I

  • CK1

  • CKI-alpha

  • casein kinase I-alpha

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-145939 BAY-888 Inhibitor 98.27% Unkown
HY-148491 CSNK1-IN-2 Inhibitor 99.22% Unkown
HY-137340 WH-10417-099 Degrader 98.14% Unkown
HY-148489 CSNK1-IN-1 Inhibitor 99.63% Unkown
HY-RS03245 CSNK1A1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-175600 MI-2-80 Degrader / Unkown
HY-RS03248 CSNK1G1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17153 Csnk1a1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21999 Csnk1g1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23603 Csnk1a1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28516 Csnk1g1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Csnk1a1 NCBI NCBI:1452