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  4. CSNK1-IN-1

CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders.

For research use only. We do not sell to patients.

CSNK1-IN-1 Chemical Structure

CSNK1-IN-1 Chemical Structure

CAS No. : 2468784-55-4

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Based on 1 publication(s) in Google Scholar

CSNK1-IN-1 Related Antibodies

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Description

CSNK1-IN-1 is a CSNK1A1 inhibitor. CSNK1-IN-1 has inhibitory activity for CSNK1A1 kinase with IC50 values of 21 μM. CSNK1-IN-1 can be used for the research of proliferative disorders[1].

IC50 & Target

IC50: 21 μM (CSNK1A1 kinase)[1]
In Vitro

CSNK1-IN-1 has inhibitory activity for CSNK1A1, CSNK1D and CSNK1A1 (in high ATP) with IC50 values of 21μM, 29.7μM and 1.5 nM, respectively[1].
CSNK1-IN-1 shows low inhibition for wild type-EGFR kinase with an IC50 value of ＞20 nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CSNK1-IN-1 Related Antibodies
Molecular Weight

533.54

Formula

C29H26F3N5O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N(CC1)C)C2=C1NC(C3=CC=NC(NC([C@@H](C4=CC=C(C=C4)F)CC(F)F)=O)=C3)=C2NC5=CC=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 4.6 mg/mL (8.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8743 mL 9.3714 mL 18.7427 mL
5 mM 0.3749 mL 1.8743 mL 3.7485 mL
View the Complete Stock Solution Preparation Table

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8743 mL 9.3714 mL 18.7427 mL 46.8568 mL
5 mM 0.3749 mL 1.8743 mL 3.7485 mL 9.3714 mL
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CSNK1-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CSNK1-IN-12468784-55-4OthersCSNK1A1inhibitoryproliferative disorderInhibitorinhibitorinhibit

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CSNK1-IN-1
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HY-148489
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