CAMK2N2 - calcium/calmodulin dependent protein kinase II inhibitor 2 Gene

Also Known as CAMKIIN; CAM-KIIN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 94032

About CAMK2N2

Cytogenetic location: 3q27.1 Genomic coordinates (GRCh38): 3:184,259,213-184,261,553 (from NCBI)

This gene has 1 transcript (splice variant), 186 orthologues and 1 paralogue. Biased expression in brain (RPKM 13.3), adrenal (RPKM 4.9) and 1 other tissue.

Summary

This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors. [provided by RefSeq, Jul 2008]

CAMK2N2 Products (1)

mRNA Protein Name
NM_033259.3 NP_150284.1 calcium/calmodulin-dependent protein kinase II inhibitor 2

CAMK2N2 Protein Structure

CaM-KIIN

CaM-KIIN: Calcium/calmodulin-dependent protein kinase II inhibitor (1 - 79)

  • 0
  • 79 a.a.
Protein Preferred Names Protein Names

calcium/calmodulin-dependent protein kinase II inhibitor 2

  • CaM-KII inhibitory protein

Related Diseases

Diseases Alias
Amyotrophic Lateral Sclerosis 21

  • Amyotrophic Lateral Sclerosis Type 21

  • ALS21

  • Multisystem Proteinopathy 5

  • Msp5

  • Distal Myopathy With Vocal Cord Weakness

  • Vcpdm

  • Myopathy, Distal, 2, Formerly

  • Mpd2, Formerly

  • Vocal Cord And Pharyngeal Dysfunction With Distal Myopathy, Formerly

  • Vcpdm, Formerly

  • Vocal Cord And Pharyngeal Distal Myopathy

  • Matr3-Related Distal Myopathy

  • Distal Myopathy 2

  • Mpd2

  • Vocal Cord And Pharyngeal Dysfunction With Distal Myopathy

  • Sclerosis, Lateral, Amyotrophic, Type 21

  • Myopathy, Distal 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01863 CAMK2N2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CAMK2N2 RGD RGD:708411
Bos taurus CAMK2N2 VGNC VGNC:26724
Mus musculus CAMK2N2 MGD MGI:1920297
Macaca mulatta CAMK2N2 VGNC VGNC:70617
Canis familiaris CAMK2N2 VGNC VGNC:38682
Others CAMK2N2 NCBI