Ubqln4 - ubiquilin 4 Gene

Also Known as A1u; A1Up; UBIN; CIP75

Species: Mus musculus

Gene Type: protein coding
Gene ID: 94232

Summary

Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of double-strand break repair via homologous recombination; regulation of cellular catabolic process; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within DNA repair and Autophagy. Located in cytosol and endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human UBQLN4 (ubiquilin 4). [provided by Alliance of Genome Resources, Apr 2022]

Ubqln4 Products (5)

mRNA Protein Name
NM_001411427.1 NP_001398356.1 ubiquilin-4 isoform 2
NM_001411428.1 NP_001398357.1 ubiquilin-4 isoform 3
NM_001411430.1 NP_001398359.1 ubiquilin-4 isoform 3
NM_001411431.1 NP_001398360.1 ubiquilin-4 isoform 3
NM_033526.3 NP_277068.1 ubiquilin-4 isoform 1

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
11162551 MGI
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
11162551 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquilin-4

  • ataxin-1 interacting ubiquitin-like protein

  • ataxin-1 ubiquitin-like interacting protein

  • ataxin-1 ubiquitin-like-interacting protein A1U

  • connexin43-interacting protein of 75 kDa

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15385 UBQLN4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ubqln4 NCBI NCBI:56893