Dcaf8 - DDB1 and CUL4 associated factor 8 Gene

Also Known as H326; Wdr42a; D1Ucla4; D1Dau35e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 98193

Summary

Predicted to be located in cytosol; mitochondrion; and nucleoplasm. Predicted to be part of Cul4-RING E3 ubiquitin Ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including brain; liver; lung; metanephros; and spleen. Human ortholog(s) of this gene implicated in giant axonal neuropathy 2. Orthologous to human DCAF8 (DDB1 and CUL4 associated factor 8). [provided by Alliance of Genome Resources, Apr 2022]

Dcaf8 Products (2)

mRNA Protein Name
NM_001357204.1 NP_001344133.1 DDB1- and CUL4-associated factor 8
NM_153555.2 NP_705783.1 DDB1- and CUL4-associated factor 8

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
31391242 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within myotube cell development IMP
IMP: Inferred from mutant phenotype
31391242 MGI
Cellular Component GO Annotation Evidence References Source
part of Cul4-RING E3 ubiquitin ligase complex IDA
IDA: Inferred from direct assay
31391242 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

DDB1- and CUL4-associated factor 8

  • WD repeat domain 42A

  • WD repeat-containing protein 42A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03568 DCAF8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dcaf8 NCBI NCBI:50717