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Cat. No.: HY-187645

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Derrubone

For research use only. We do not sell to patients.

CAS No.: 22044-58-2
Formula: C₂₁H₁₈O₆
Molecular Weight:366.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Derrubone Chemical Structure

CAS No.: 22044-58-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC50	11.9 μM	Antiproliferative activity against human MCF-7 breast cancer cells assessed as reduction in cell viability incubated for 72 hrs by MTS/PMS cell proliferation assay. Antiproliferative activity against human MCF-7 breast cancer cells assessed as reduction in cell viability incubated for 72 hrs by MTS/PMS cell proliferation assay.	18154304
HCT-116	IC50	13.7 μM	Antiproliferative activity against human HCT-116 colon cancer cells assessed as reduction in cell viability incubated for 72 hrs by MTS/PMS cell proliferation assay. Antiproliferative activity against human HCT-116 colon cancer cells assessed as reduction in cell viability incubated for 72 hrs by MTS/PMS cell proliferation assay.	18154304
MCF7	IC50	9 μM	Antiproliferative activity against human MCF-7 breast cancer cells. Antiproliferative activity against human MCF-7 breast cancer cells.	18020309
SK-BR-3	IC50	12 μM	Antiproliferative activity against human SkBr3 breast cancer cells. Antiproliferative activity against human SkBr3 breast cancer cells.	18020309
SK-BR-3	IC50	14.0 μM	Induction of Hsp90 client protein Her2 degradation in SkBr3 human breast cancer cells incubated for 24 h measured by ELISA assay. Induction of Hsp90 client protein Her2 degradation in SkBr3 human breast cancer cells incubated for 24 h measured by ELISA assay.	18020309

Chemical Information

CAS No. 22044-58-2
Molecular Weight 366.36
Formula C₂₁H₁₈O₆
SMILES

O=C1C(C2=CC3=C(OCO3)C=C2)=COC4=CC(O)=C(C/C=C(C)\C)C(O)=C14
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

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100 mg

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