CETP - cholesteryl ester transfer protein Gene
Also Known as BPIFF; HDLCQ10
Species: Homo sapiens
About CETP
This gene has 5 transcripts (splice variants), 138 orthologues, 12 paralogues and is associated with 2 phenotypes. Biased expression in spleen (RPKM 19.4), fat (RPKM 13.4) and 8 other tissues.
Summary
The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to Other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
CETP Products (5)
| mRNA | Protein | Name |
|---|---|---|
| NM_000078.3 | NP_000069.2 | cholesteryl ester transfer protein isoform 1 precursor |
| NM_001286085.2 | NP_001273014.1 | cholesteryl ester transfer protein isoform 2 precursor |
| XM_006721124.4 | XP_006721187.1 | cholesteryl ester transfer protein isoform X1 |
| NM_000078.3 | NP_000069.2 | cholesteryl ester transfer protein isoform 1 precursor |
| NM_001286085.2 | NP_001273014.1 | cholesteryl ester transfer protein isoform 2 precursor |
CETP Protein Structure
LBP_BPI_CETP: LBP / BPI / CETP family, N-terminal domain (36 - 209)
LBP_BPI_CETP_C: LBP / BPI / CETP family, C-terminal domain (243 - 480)
- 0
- 100
- 200
- 300
- 400
- 493 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
cholesteryl ester transfer protein |
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|
CETP Antibodies
| Cat. No. | Product Name | Application | Reactivity |
|---|---|---|---|
| HY-P83236 | CETP Antibody (YA2981) | WB, IP | Human |
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Myocardial Infarction |
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| Hypoalphalipoproteinemia, Primary, 1 |
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| Lipoprotein Quantitative Trait Locus |
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| Vascular Disease |
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| Hyperlipoproteinemia, Type Iii |
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| Familial Hypercholesterolemia |
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| Sitosterolemia |
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| Non-Alcoholic Fatty Liver Disease |
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| Nephrotic Syndrome |
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| Hyperlipidemia, Familial Combined, 3 |
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| Type 2 Diabetes Mellitus |
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| Atherosclerosis Susceptibility |
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| Coronary Stenosis |
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| Familial Hyperlipidemia |
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| Hypoalphalipoproteinemia, Primary, 2 |
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| Prediabetes Syndrome |
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| Macular Degeneration, Age-Related, 1 |
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| Hypolipoproteinemia |
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| Primary Biliary Cholangitis |
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| Abetalipoproteinemia |
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| Food Allergy |
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| Allergic Disease |
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| Alzheimer Disease, Familial, 1 |
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| Peripheral Vascular Disease |
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| Hypertriglyceridemia 1 |
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| Hypertension, Essential |
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| Coronary Heart Disease 1 |
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| Hypoalphalipoproteinemia |
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| Lipid Metabolism Disorder |
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| Aortic Aneurysm, Familial Abdominal, 1 |
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| Cerebrovascular Disease |
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| Diabetes Mellitus |
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| Hypercholesterolemia, Familial, 1 |
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| Tangier Disease |
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| Hypothyroidism |
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| Heart Disease |
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| Cardiovascular System Disease |
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| Basilar Artery Insufficiency |
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| Coronary Restenosis |
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| Body Mass Index Quantitative Trait Locus 11 |
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| Aortic Atherosclerosis |
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| Hyperlipoproteinemia, Type Iv |
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| Hyperalphalipoproteinemia 1 |
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