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Cat. No.: HY-N8641

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Kadsulignan N

Kadsulignan N, a natural product has anti-HIV activity (EC₅₀: 43.56 μM). Kadsulignan N is also a COX-2 ligand (K_i: 72.24 nM).

For research use only. We do not sell to patients.

CAS No.: 163564-58-7
Formula: C₂₄H₃₀O₇
Molecular Weight:430.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (278 KB)

Kadsulignan N Chemical Structure

CAS No.: 163564-58-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Kadsulignan N, a natural product has anti-HIV activity (EC₅₀: 43.56 μM). Kadsulignan N is also a COX-2 ligand (K_i: 72.24 nM)^[1]^[2].

IC₅₀ & Target^[2]

COX-2

All HIV Isoforms :

All COX Isoforms :

In Vitro

Kadsulignans N shows weak inhibitory activitie against COX-2, with IC₅₀ value of 600.54 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 163564-58-7
Molecular Weight 430.49
Formula C₂₄H₃₀O₇
SMILES

C[C@@H]1[C@H](C)[C@H]2C3=CC(OC)=C(OC)C(OC)=C3C4=C(OC)C(OC)=C(OC)C=C4[C@@H]1O2
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gao XM, et al. Lignans from Kadsura angustifolia. J Nat Prod. 2008 Apr;71(4):558-63. [Content Brief]

[2]. Zhang XY, et al. Discovery of cyclooxygenase-2 inhibitors from Kadsura coccinea by affinity ultrafiltration mass spectrometry and the anti-inflammatory activity. Fitoterapia. 2021 Jun;151:104872. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Kadsulignan N

All HIV Isoforms

All COX Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Kadsulignan N Related Classifications

HY-N8641 Related Classifications