163564-58-7
163564-58-7
Chemical Structure
Kadsulignan N
- CAS No.: 163564-58-7
- Formula:C24H30O7
- Molecular Weight:430.49
IUPAC Name: (5R,6R,7S,8S)-1,2,3,10,11,12-hexamethoxy-6,7-dimethyl-5,6,7,8-tetrahydro-5,8-epoxydibenzo[a,c][8]annulene
InChIKey: RRQAIPQPPCAEHD-JARDSOJUSA-N
SMILES: C[C@@H]1[C@H](C)[C@H]2C3=CC(OC)=C(OC)C(OC)=C3C4=C(OC)C(OC)=C(OC)C=C4[C@@H]1O2
Biological Activity: Kadsulignan N, a natural product has anti-HIV activity (EC50: 43.56 μM). Kadsulignan N is also a COX-2 ligand (Ki: 72.24 nM)[1][2].
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Kadsulignan N | Kadsulignan N, a natural product has anti-HIV activity (EC50: 43.56 μM). Kadsulignan N is also a COX-2 ligand (Ki: 72.24 nM). | |||||||||||||||||||||
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References
- [1]. Gao XM, et al. Lignans from Kadsura angustifolia. J Nat Prod. 2008 Apr;71(4):558-63. [Content Brief]
- [2]. Zhang XY, et al. Discovery of cyclooxygenase-2 inhibitors from Kadsura coccinea by affinity ultrafiltration mass spectrometry and the anti-inflammatory activity. Fitoterapia. 2021 Jun;151:104872. [Content Brief]
Keywords
