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United States

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製品番号: HY-146121

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Antitubercular agent-26

Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC₅₀ of 0.50 μM and an intracellular IC₅₀ of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 1845720-46-8
分子式: C₂₂H₂₃N₅O₃S₂
分子量:469.58

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

Antitubercular agent-26 構造式

CAS 番号: 1845720-46-8

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>50 μM Compound: 32	Cytotoxicity against human A549 cells assessed as inhibition of cell growth Cytotoxicity against human A549 cells assessed as inhibition of cell growth	[PMID: 33075682]
HEK293	IC₅₀	>50 μM Compound: 32	Cytotoxicity against HEK293 cells assessed as inhibition of cell growth Cytotoxicity against HEK293 cells assessed as inhibition of cell growth	[PMID: 33075682]
HepG2	IC₅₀	>50 μM Compound: 32	Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth	[PMID: 33075682]
Jurkat	IC₅₀	>50 μM Compound: 32	Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth Cytotoxicity against human Jurkat cells assessed as inhibition of cell growth	[PMID: 33075682]

化学情報

CAS 番号 1845720-46-8
分子量 469.58
分子式 C₂₂H₂₃N₅O₃S₂
SMILES

O=C(C(S1)=CC2=C1N=C(N3CCC(C(N(C)C)=O)CC3)S2)NC4=CC=C(OC(C)=N5)C5=C4
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (276 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Jin G, et al. Discovery of thienothiazolocarboxamide analogues as novel anti-tubercular agent. Bioorg Med Chem. 2020 Dec 1;28(23):115797. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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