1845720-46-8
Chemical Structure
Antitubercular agent-26
- CAS No.: 1845720-46-8
- Formula:C22H23N5O3S2
- Molecular Weight:469.58
IUPAC Name: 2-(4-(dimethylcarbamoyl)piperidin-1-yl)-N-(2-methylbenzo[d]oxazol-5-yl)thieno[2,3-d]thiazole-5-carboxamide
InChIKey: AIMDOKRPWXBXFC-UHFFFAOYSA-N
SMILES: O=C(C(S1)=CC2=C1N=C(N3CCC(C(N(C)C)=O)CC3)S2)NC4=CC=C(OC(C)=N5)C5=C4
Biological Activity: Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC50 of 0.50 μM and an intracellular IC50 of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity[1].
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Antitubercular agent-26 | Antitubercular agent-26 (Compound 32) is an orally active anti-tubercular agent with an extracellular IC50 of 0.50 μM and an intracellular IC50 of 0.51 μM against M. tuberculosis H37Rv. Antitubercular agent-26 shows good metabolic stability, low risk of cardiotoxicity and no genotoxicity. | |||||||||||||||||||||
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Keywords
