DosatiLink-2
DosatiLink-2 is an Abelson murine leukemia (ABL) enzyme inhibitor.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2941512-38-3
- 分子式: C65H85Cl2F2N13O15S
- 分子量:1429.42
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| K562 | EC50 |
>300 nM
Compound: Dosati Link-2
|
Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
Antiproliferative activity against human K562 cells expressing ABL T315I mutant assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
|
[PMID: 37849551] |
| K562 | EC50 |
2.49 nM
Compound: Dosati Link-2
|
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
Antiproliferative activity against human K562 cells assessed as inhibition of cell growth incubated for 3 days by celltiter-glo 2.0 assay
|
[PMID: 37849551] |
化学情報
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CAS 番号 2941512-38-3
-
分子量 1429.42
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分子式 C65H85Cl2F2N13O15S
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SMILES
O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(C1CCN(C2=C(C3=CC=NN3)C=C(C(NC4=CC=C(OC(F)(Cl)F)C=C4)=O)C=N2)CC1)=O)N5CCN(C6=CC(NC7=NC=C(C(NC8=C(Cl)C=CC=C8C)=O)S7)=NC(C)=N6)CC5
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)