RDH13 - retinol dehydrogenase 13 Gene

Also Known as SDR7C3

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 112724

About RDH13

This gene has 23 transcripts (splice variants), 1 gene allele, 174 orthologues and 4 paralogues. Ubiquitous expression in skin (RPKM 5.7), stomach (RPKM 4.2) and 25 other tissues.

Summary

This gene encodes a mitochondrial short-chain dehydrogenase/reductase, which catalyzes the reduction and oxidation of retinoids. The encoded enzyme may function in retinoic acid production and may also protect the mitochondria against oxidative stress. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]

RDH13 Products (2)

mRNA Protein Name
NM_001145971.2 NP_001139443.1 retinol dehydrogenase 13 isoform 1 precursor
NM_138412.4 NP_612421.1 retinol dehydrogenase 13 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables all-trans-retinol dehydrogenase (NADP+) activity IDA
IDA: Inferred from direct assay
18039331 GOA
Biological Process GO Annotation Evidence 参考文献 由来
involved in retinal metabolic process IDA
IDA: Inferred from direct assay
18039331 GOA
Cellular Component GO Annotation Evidence 参考文献 由来
located in mitochondrial inner membrane IDA
IDA: Inferred from direct assay
18039331 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RDH13 Protein Structure

adh_short

adh_short: short chain dehydrogenase (39 - 180)

  • 0
  • 100
  • 200
  • 300
  • 331 a.a.
Protein Preferred Names Protein Names

retinol dehydrogenase 13

  • retinol dehydrogenase 13 (all-trans and 9-cis)

関連疾患

Diseases Alias
Noonan Syndrome 10

  • NS10

  • Noonan Syndrome, Type 10
Fundus Albipunctatus

  • Retinitis Punctata Albescens

  • Pigmentary Retinal Dystrophy

  • RPA

  • Albipunctate Retinal Dystrophy

  • Lauber'S Disease

  • FALBI

  • Fa
Leber Plus Disease

  • Leber Congenital Amaurosis

  • Lca

  • Leber'S Amaurosis

  • Leber'S Disease

  • Amaurosis Congenita Of Leber

  • Amaurosis Congenita Of Leber, Type 1

  • Lhon Plus Disease

  • Congenital Absence Of The Rods And Cones

  • Congenital Retinal Blindness

  • Crb

  • Congenital Amaurosis Of Retinal Origin

  • Leber'S Congenital Amaurosis

  • Leber Congenital Amaurosis 1

  • Leber'S Congenital Tapetoretinal Degeneration

  • Leber'S Congenital Tapetoretinal Dysplasia

  • Lca1

  • Leber Congenital Amaurosis Type 1

  • Retinal Blindness, Congenital

  • Amaurosis, Leber Congenital

  • Dysgenesis Neuroepithelialis Retinae

  • Hereditary Epithelial Dysplasia Of Retina

  • Hereditary Retinal Aplasia

  • Heredoretinopathia Congenitalis

  • Leber Abiotrophy

  • Leber Congenital Tapetoretinal Degeneration

  • Lebers Congenital Amaurosis

  • Optic Atrophy, Hereditary, Leber
Fundus Dystrophy

  • Retinal Dystrophy

  • Retinal Dystrophies

  • Dystrophy, Retinal
Retinitis Pigmentosa

  • RP

  • Rod-Cone Dystrophy

  • Autosomal Recessive Retinitis Pigmentosa

  • Non-Syndromic Retinitis Pigmentosa

  • Pericentral Pigmentary Retinopathy

  • Pigmentary Retinopathy

  • Tapetoretinal Degeneration

  • Rcd

  • Retinitis Pigmentosa Autosomal Recessive

  • ARRP

  • Retinitis Pigmentosa, Autosomal Recessive

  • Retinitis Pigmentosa 1
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11801 RDH13 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris RDH13 VGNC VGNC:45453
Bos taurus RDH13 VGNC VGNC:33842
Felis catus RDH13 VGNC VGNC:97601
Mus musculus RDH13 MGD MGI:1918732
Rattus norvegicus RDH13 RGD RGD:1304959
Others RDH13 NCBI