PRPF39 - pre-mRNA processing factor 39 Gene

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 55015

About PRPF39

Cytogenetic location: 14q21.2 Genomic coordinates (GRCh38): 14:45,084,116-45,116,282 (from NCBI)

This gene has 12 transcripts (splice variants) and 210 orthologues. Ubiquitous expression in skin (RPKM 15.3), prostate (RPKM 14.2) and 25 other tissues.

Summary

Predicted to be involved in mRNA 5'-splice site recognition. Predicted to be part of U1 snRNP; U2-type prespliceosome; and commitment complex. [provided by Alliance of Genome Resources, Apr 2022]

PRPF39 Products (1)

mRNA Protein Name
NM_017922.4 NP_060392.3 pre-mRNA-processing factor 39

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pre-mRNA-processing factor 39

  • PRP39 homolog

PRPF39 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
PRPF39 Q86UA1 ATN1 Homo sapiens Q86V38
Y2H Pooling
32814053
Intra
PRPF39 Q86UA1 ATN1 Homo sapiens Q86V38
Validated Y2H
32814053
Intra
PRPF39 Q86UA1 ATN1 Homo sapiens Q86V38
Y2H Array
32814053
Intra
PRPF39 Q86UA1 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra
PRPF39 Q86UA1 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra
PRPF39 Q86UA1 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra
PRPF39 Q86UA1 SMN1 Homo sapiens Q16637
Y2H Pooling
32814053
Intra
PRPF39 Q86UA1 SMN1 Homo sapiens Q16637
Validated Y2H
32814053
Intra
PRPF39 Q86UA1 SMN1 Homo sapiens Q16637
Y2H Array
32814053
Intra
PRPF39 Q86UA1 TOLLIP Homo sapiens Q9H0E2
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Schindler Disease

  • Alpha-N-Acetylgalactosaminidase Deficiency

  • Naga Deficiency

  • Alpha-Galactosidase B Deficiency

  • Alpha-Galnac Deficiency, Schindler Type

  • Alpha-Naga Deficiency

  • Angiokeratoma Corporis Diffusum-Glycopeptiduria

  • Galb Deficiency

  • Kanzaki Disease

  • Lysosomal Glycoaminoacid Storage Disease-Angiokeratoma Corporis Diffusum

  • Neuroaxonal Dystrophy, Schindler Type

  • Neuronal Axonal Dystrophy, Schindler Type

  • Schindler Disease, Type I

  • Schindler Disease, Type Ii
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11210 PRPF39 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus PRPF39 VGNC VGNC:33377
Mus musculus PRPF39 MGD MGI:104602
Felis catus PRPF39 VGNC VGNC:64373
Rattus norvegicus PRPF39 RGD RGD:1308702
Macaca mulatta PRPF39 VGNC VGNC:76292
Canis familiaris PRPF39 VGNC VGNC:45024
Others PRPF39 NCBI