NCEH1 - neutral cholesterol ester hydrolase 1 Gene

Also Known as NCEH; AADACL1

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 57552

About NCEH1

Cytogenetic location: 3q26.31 Genomic coordinates (GRCh38): 3:172,630,249-172,711,067 (from NCBI)

This gene has 6 transcripts (splice variants), 279 orthologues and 5 paralogues. Ubiquitous expression in brain (RPKM 15.5), adrenal (RPKM 10.5) and 23 other tissues.

Summary

Predicted to enable hydrolase activity. Predicted to be involved in ether lipid metabolic process. Predicted to act upstream of or within SMAD protein signal transduction; protein dephosphorylation; and xenobiotic metabolic process. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]

NCEH1 Products (4)

mRNA Protein Name
NM_001146276.3 NP_001139748.2 neutral cholesterol ester hydrolase 1 isoform a
NM_001146277.3 NP_001139749.1 neutral cholesterol ester hydrolase 1 isoform c
NM_001146278.3 NP_001139750.1 neutral cholesterol ester hydrolase 1 isoform c
NM_020792.6 NP_065843.4 neutral cholesterol ester hydrolase 1 isoform b

NCEH1 Protein Structure

Abhydrolase_3

Abhydrolase_3: alpha/beta hydrolase fold (141 - 302)

Abhydrolase_3

Abhydrolase_3: alpha/beta hydrolase fold (361 - 421)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 448 a.a.
Protein Preferred Names Protein Names

neutral cholesterol ester hydrolase 1

  • 2-acetyl MAGE hydrolase

関連疾患

Diseases Alias
Niemann-Pick Disease, Type C2

  • NPC2

  • Niemann-Pick Disease Type C2

  • Niemann-Pick C2 Disease

  • Niemann-Pick Disease C2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09076 NCEH1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19463 Nceh1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25956 Nceh1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Bos taurus NCEH1 VGNC VGNC:31911
Macaca mulatta NCEH1 VGNC VGNC:81478
Felis catus NCEH1 VGNC VGNC:97522
Rattus norvegicus NCEH1 RGD RGD:1311104
Canis familiaris NCEH1 VGNC VGNC:43649
Mus musculus NCEH1 MGD MGI:2443191
Others NCEH1 NCBI