Mre11 - MRE11 homolog, double strand break repair nuclease Gene

Also Known as Mre11a

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 64046

Summary

Predicted to enable identical protein binding activity; nuclease activity; and protein C-terminus binding activity. Predicted to contribute to DNA binding activity and DNA helicase activity. Involved in heart development and negative regulation of viral entry into host cell. Located in chromatin; nuclear lumen; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in breast carcinoma; endometrial cancer; stomach carcinoma; and urinary bladder Cancer. Orthologous to human MRE11 (MRE11 homolog, double strand break repair nuclease). [provided by Alliance of Genome Resources, Apr 2022]

Mre11 Products (2)

mRNA Protein Name
NM_022279.1 NP_071615.1 double-strand break repair protein MRE11
NM_022279.1 NP_071615.1 double-strand break repair protein MRE11

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
18212738 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in heart development IEP
IEP: Inferred from expression pattern
10908350 RGD
involved in negative regulation of viral entry into host cell IMP
IMP: Inferred from mutant phenotype
22850678 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in chromatin IDA
IDA: Inferred from direct assay
10855503 RGD
located in condensed nuclear chromosome IDA
IDA: Inferred from direct assay
10855503 RGD
located in nucleoplasm IDA
IDA: Inferred from direct assay
16706843 RGD
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
18212738 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

double-strand break repair protein MRE11

  • MRE11 homolog 1

  • MRE11 homolog A, double strand break repair nuclease

  • MRE11 homolog, double strand break repair nuclease A

  • MRE11 meiotic recombination 11 homolog A

  • double-strand break repair protein MRE11A

  • meiotic recombination 11 homolog 1

  • meiotic r

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-19959 Mirin 99.63% Unkown
HY-117693 (E/Z)-Mirin Inhibitor 99.22% Unkown
HY-116770 PFM01 Inhibitor 99.91% Unkown
HY-120951 PFM39 Inhibitor 98.18% Unkown
HY-148078 PFM03 Inhibitor 99.86% Unkown
HY-170844 MU147 Inhibitor 99.35% Unkown
HY-170845 MU1409 Inhibitor 98.52% Unkown
HY-RS08643 MRE11 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-148302 LT-626 Inhibitor / Unkown
HY-149972 Antitumor agent-96 Inducer / Unkown
HY-RS24170 Mre11 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Mre11 NCBI NCBI:4361