RBKS - ribokinase Gene

Also Known as RK; RBSK

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 64080

About RBKS

Cytogenetic location: 2p23.2 Genomic coordinates (GRCh38): 2:27,781,379-27,890,387 (from NCBI)

This gene has 4 transcripts (splice variants), 199 orthologues and 3 paralogues. Broad expression in adrenal (RPKM 7.1), small intestine (RPKM 6.5) and 22 other tissues.

Summary

This gene encodes a member of the carbohydrate kinase PfkB family. The encoded protein phosphorylates ribose to form ribose-5-phosphate in the presence of ATP and magnesium as a first step in ribose metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

RBKS Products (2)

mRNA Protein Name
NM_001287580.2 NP_001274509.1 ribokinase isoform 2
NM_022128.3 NP_071411.1 ribokinase isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables identical protein binding IPI
IPI: Inferred from physical interaction
31515488 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
21044950 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RBKS Protein Structure

PfkB

PfkB: pfkB family carbohydrate kinase (17 - 312)

  • 0
  • 100
  • 200
  • 300
  • 322 a.a.
Protein Preferred Names Protein Names

ribokinase

RBKS Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
RBKS Q9H477 NSF Homo sapiens P46459
Anti Tag CoIP
28514442
Intra
RBKS Q9H477 RBKS Homo sapiens Q9H477
Y2H Prey Pooling
32296183
Intra
RBKS Q9H477 RPS4Y1 Homo sapiens P22090
Anti Tag CoIP
33961781
Intra
RBKS Q9H477 RBKS Homo sapiens Q9H477
Y2H Array
32296183
Intra
RBKS Q9H477 ACD Homo sapiens Q96AP0
Pull Down
21044950
Intra
RBKS Q9H477 ACD Homo sapiens Q96AP0
BiFC
21044950
Intra
RBKS Q9H477 RBKS Homo sapiens Q9H477
Validated Y2H
32296183
Intra
RBKS Q9H477 PTGR3 Homo sapiens Q8N4Q0
Anti Tag CoIP
33961781
Intra
RBKS Q9H477 NAPA Homo sapiens P54920
Anti Tag CoIP
33961781
Intra
RBKS Q9H477 RBKS Homo sapiens Q9H477
Y2H Array
31515488
Intra
RBKS Q9H477 TUBB2B Homo sapiens Q9BVA1
Anti Tag CoIP
33961781
Intra
RBKS Q9H477 NSF Homo sapiens P46459
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant RBKS Proteins

製品番号 製品名 アクセッション番号 純度
HY-P76564 RBKS Protein, Human (His) Q9H477-1 (M1-F322) ≥ 85%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS11728 RBKS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19635 Rbks Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26130 Rbks Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Macaca mulatta RBKS VGNC VGNC:76575
Rattus norvegicus RBKS RGD RGD:1310064
Canis familiaris RBKS VGNC VGNC:45401
Mus musculus RBKS MGD MGI:1918586
Bos taurus RBKS VGNC VGNC:33780
Felis catus RBKS VGNC VGNC:64518
Others RBKS NCBI