Lmf1 - lipase maturation factor 1 Gene

Also Known as cld; Tmem112; 2400010G15Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 76483

Summary

Acts upstream of or within several processes, including positive regulation of lipoprotein Lipase activity; protein glycosylation in Golgi; and regulation of lipid metabolic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including 1st branchial arch mandibular component; adipose tissue; central nervous system; liver; and vertebral cartilage condensation. Human ortholog(s) of this gene implicated in familial Lipase maturation factor 1 deficiency. Orthologous to human LMF1 (Lipase maturation factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Lmf1 Products (1)

mRNA Protein Name
NM_029624.4 NP_083900.3 lipase maturation factor 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within chylomicron remnant clearance IMP
IMP: Inferred from mutant phenotype
6857276 MGI
acts upstream of or within endoplasmic reticulum to Golgi vesicle-mediated transport IMP
IMP: Inferred from mutant phenotype
2211673 MGI
acts upstream of or within positive regulation of lipoprotein lipase activity IDA
IDA: Inferred from direct assay
17994020 MGI
acts upstream of or within positive regulation of lipoprotein lipase activity IMP
IMP: Inferred from mutant phenotype
2211673 MGI
acts upstream of or within protein glycosylation IMP
IMP: Inferred from mutant phenotype
8694753 MGI
acts upstream of or within protein maturation IDA
IDA: Inferred from direct assay
17994020 MGI
acts upstream of or within protein secretion IMP
IMP: Inferred from mutant phenotype
11714855 MGI
acts upstream of or within regulation of cholesterol metabolic process IMP
IMP: Inferred from mutant phenotype
6857276 MGI
acts upstream of or within regulation of triglyceride metabolic process IMP
IMP: Inferred from mutant phenotype
6857276 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
17994020 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lipase maturation factor 1

  • transmembrane protein 112

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS07711 LMF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Lmf1 NCBI NCBI:64788