Sytl2 - synaptotagmin-like 2 Gene
Also Known as Slp2; mKIAA1597
生物種: Mus musculus
Summary
Enables neurexin family protein binding activity. Involved in exocytosis and positive regulation of mucus secretion. Acts upstream of or within protein localization to plasma membrane. Located in melanosome and plasma membrane. Is extrinsic component of plasma membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human SYTL2 (synaptotagmin like 2). [provided by Alliance of Genome Resources, Apr 2022]
Sytl2 Products (9)
| mRNA | Protein | Name |
|---|---|---|
| NM_001040085.2 | NP_001035174.1 | synaptotagmin-like protein 2 isoform 2 |
| NM_001040087.2 | NP_001035176.1 | synaptotagmin-like protein 2 isoform 4 |
| NM_001040088.2 | NP_001035177.1 | synaptotagmin-like protein 2 isoform 5 |
| NM_001289583.1 | NP_001276512.1 | synaptotagmin-like protein 2 isoform 6 |
| NM_001289584.1 | NP_001276513.1 | synaptotagmin-like protein 2 isoform 7 |
| NM_001289585.1 | NP_001276514.1 | synaptotagmin-like protein 2 isoform 8 |
| NM_001289586.1 | NP_001276515.1 | synaptotagmin-like protein 2 isoform 4 |
| NM_001368878.1 | NP_001355807.1 | synaptotagmin-like protein 2 isoform 9 |
| NM_031394.3 | NP_113571.2 | synaptotagmin-like protein 2 isoform 3 |
| Molecular Function GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| enables neurexin family protein binding |
IDA
IDA: Inferred from direct assay
|
11243866 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
12590134 | MGI |
| Biological Process GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| involved in exocytosis |
IDA
IDA: Inferred from direct assay
|
18266782 | MGI |
| involved in positive regulation of mucus secretion |
IMP
IMP: Inferred from mutant phenotype
|
16716193 | MGI |
| acts upstream of or within protein localization to plasma membrane |
IDA
IDA: Inferred from direct assay
|
24284068 | MGI |
| Cellular Component GO Annotation | Evidence | 参考文献 | 由来 |
|---|---|---|---|
| located in melanosome |
IDA
IDA: Inferred from direct assay
|
11773082 | MGI |
| located in membrane |
IDA
IDA: Inferred from direct assay
|
11243866 | MGI |
| located in plasma membrane |
IDA
IDA: Inferred from direct assay
|
11243866 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
synaptotagmin-like protein 2 |
|