Herkinorin
Based on 2 publication(s) in Google Scholar
Herkinorin is a potent and selective agonist of µ opioid receptor with a Ki of 45 nM Herkinorin is widely used for pain research.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 862073-77-6
- 分子式: C28H30O8
- 分子量:494.53
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Herkinorin
MoreOpioid Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | EC50 |
1320 nM
Compound: 1c
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Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay
Agonist activity at human recombinant kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay
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[PMID: 18380425] |
| CHO | EC50 |
1320 nM
Compound: 13
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Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor kappa1 expressed in CHO cells
Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor kappa1 expressed in CHO cells
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[PMID: 16033256] |
| CHO | EC50 |
500 nM
Compound: 1c
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Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay
Agonist activity at human recombinant mu opioid receptor expressed in CHO cells by [35S]GTP-gamma-S binding assay
|
[PMID: 18380425] |
| CHO | EC50 |
500 nM
Compound: 13
|
Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor mu1 expressed in CHO cells
Stimulation of [35S]GTP-gamma-S, binding to Opioid receptor mu1 expressed in CHO cells
|
[PMID: 16033256] |
化学情報
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CAS 番号 862073-77-6
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分子量 494.53
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分子式 C28H30O8
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SMILES
O=C([C@H](C[C@H](OC(C1=CC=CC=C1)=O)C([C@@]23[H])=O)[C@]2(C)CC[C@@]([C@]3(C)C[C@@H](C4=COC=C4)O5)([H])C5=O)OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Int Immunopharmacol
Herkinorin ameliorates neuronal damage in a pentylenetetrazol-induced epilepsy rat model through altering microglial and astrocytic activation by inhibiting PARP1 and NF-κB. [Abstract]2025 May 16:155:114588. PMID: 40209309 -
Neurochem Res
Herkinorin Exerted Neuroprotective Effects After Spinal Cord Injury by Suppression of NF-κB Pathway Activation. [Abstract]2026 Jun 1;51(3):180. PMID: 42219409
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Herkinorin 関連分類
HY-121415 関連分類
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